| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuraminidase |
|---|
| Ligand | BDBM50068270 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_698045 (CHEMBL1645796) |
|---|
| IC50 | 12400±n/a nM |
|---|
| Citation |  Dao, TT; Nguyen, PH; Lee, HS; Kim, E; Park, J; Lim, SI; Oh, WK Chalcones as novel influenza A (H1N1) neuraminidase inhibitors from Glycyrrhiza inflata. Bioorg Med Chem Lett21:294-8 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuraminidase |
|---|
| Name: | Neuraminidase |
|---|
| Synonyms: | NA | NRAM_I33A0 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 49687.56 |
|---|
| Organism: | Influenza A virus |
|---|
| Description: | ChEMBL_1347422 |
|---|
| Residue: | 453 |
|---|
| Sequence: | MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGIITYNVVA
GQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQ
GALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGIS
GPDNGAVAVLKYNGIITETIKSWRKKILRTQESECTCVNGSCFTIMTDGPSNGLASYKIF
KIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGY
ICSGVFGDNPRPKDGPGSCGPVSADGANGVKGFSYRYGNGVWIGRTKSDSSRHGFEMIWD
PNGWTETDSRFSVRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPEEETI
WTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
|
|
|
|---|
| BDBM50068270 |
|---|
| n/a |
|---|
| Name | BDBM50068270 |
|---|
| Synonyms: | (E)-3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one | (E)-3-[5-(1,1-Dimethyl-allyl)-4-hydroxy-2-methoxy-phenyl]-1-(4-hydroxy-phenyl)-propenone | 3-(4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one | 3-[5-((E)-1,1-Dimethyl-allyl)-4-hydroxy-2-methoxy-phenyl]-1-(4-hydroxy-phenyl)-propenone | CHEMBL139702 | Licochalcone A |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H22O4 |
|---|
| Mol. Mass. | 338.397 |
|---|
| SMILES | COc1cc(O)c(cc1\C=C\C(=O)c1ccc(O)cc1)C(C)(C)C=C |
|---|
| Structure | 
|
|---|
Search and Browse
