| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50484519 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_791578 (CHEMBL1930715) |
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| IC50 | >47000±n/a nM |
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| Citation |  Hu, L; Zhang, S; He, X; Luo, Z; Wang, X; Liu, W; Qin, X Design and synthesis of novel ?-diketo derivatives as HIV-1 integrase inhibitors. Bioorg Med Chem20:177-82 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | pol |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32203.43 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_106649 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED
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| BDBM50484519 |
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| n/a |
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| Name | BDBM50484519 |
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| Synonyms: | CHEMBL1928160 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22FN3O5 |
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| Mol. Mass. | 427.4256 |
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| SMILES | COc1cc(cc(OC)c1OC)C(\O)=C\C(=O)c1nnn(Cc2ccc(F)cc2)c1C |
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| Structure | 
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