| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50485688 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_854340 (CHEMBL2154560) |
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| IC50 | 1.1±n/a nM |
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| Citation |  Ma, XD; He, QQ; Zhang, X; Yang, SQ; Yang, LM; Gu, SX; Zheng, YT; Chen, FE; Dai, HF Synthesis, structure-activity relationships, and docking studies of N-phenylarylformamide derivatives (PAFAs) as non-nucleoside HIV reverse transcriptase inhibitors. Eur J Med Chem58:504-12 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM50485688 |
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| n/a |
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| Name | BDBM50485688 |
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| Synonyms: | CHEMBL2151836 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H24ClN3O5S |
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| Mol. Mass. | 501.982 |
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| SMILES | Cc1ccc(cc1C)C(=O)Nc1cc(Cl)ccc1OCC(=O)Nc1ccc(cc1C)S(N)(=O)=O |
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| Structure | 
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