| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50029787 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_201913 (CHEMBL880938) |
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| Ki | 1.71±n/a nM |
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| Citation |  Bertha, CM; Vilner, BJ; Mattson, MV; Bowen, WD; Becketts, K; Xu, H; Rothman, RB; Flippen-Anderson, JL; Rice, KC (E)-8-benzylidene derivatives of 2-methyl-5-(3-hydroxyphenyl)morphans: highly selective ligands for the sigma 2 receptor subtype. J Med Chem38:4776-85 (1996) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50029787 |
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| n/a |
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| Name | BDBM50029787 |
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| Synonyms: | 5-(3-Hydroxy-phenyl)-8-[1-(4-iodo-phenyl)-meth-(E)-ylidene]-2-methyl-2-aza-bicyclo[3.3.1]nonan-7-one | CHEMBL145422 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22INO2 |
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| Mol. Mass. | 459.3201 |
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| SMILES | CN1CCC2(CC1C(=Cc1ccc(I)cc1)C(=O)C2)c1cccc(O)c1 |w:8.9| |
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| Structure | 
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