| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50030220 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_195686 (CHEMBL800603) |
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| IC50 | 7900±n/a nM |
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| Citation |  Mohan, P; Loya, S; Avidan, O; Verma, S; Dhindsa, GS; Wong, MF; Huang, PP; Yashiro, M; Baba, M; Hizi, A Synthesis of naphthalenesulfonic acid small molecules as selective inhibitors of the DNA polymerase and ribonuclease H activities of HIV-1 reverse transcriptase. J Med Chem37:2513-9 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50030220 |
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| n/a |
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| Name | BDBM50030220 |
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| Synonyms: | 4-[(10R,13R)-17-(1,5-Dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yloxycarbonylamino]-5-hydroxy-naphthalene-2,7-disulfonic acid | CHEMBL312014 |
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| Type | Small organic molecule |
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| Emp. Form. | C38H53NO9S2 |
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| Mol. Mass. | 731.959 |
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| SMILES | CC(C)CCCC(C)C1CCC2C3CC=C4CC(CC[C@]4(C)C3CC[C@]12C)OC(=O)Nc1cc(cc2cc(cc(O)c12)S(O)(=O)=O)S(O)(=O)=O |t:14| |
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| Structure | 
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