| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor beta |
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| Ligand | BDBM50031458 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_195640 (CHEMBL795958) |
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| IC50 | 8±n/a nM |
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| Citation |  Alam, M; Zhestkov, V; Sani, BP; Venepally, P; Levin, AA; Kazmer, S; Li, E; Norris, AW; Zhang, XK; Lee, MO Conformationally defined 6-s-trans-retinoic acid analogs. 2. Selective agonists for nuclear receptor binding and transcriptional activity. J Med Chem38:2302-10 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor beta |
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| Name: | Retinoic acid receptor beta |
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| Synonyms: | Nr1b2 | Nuclear receptor subfamily 1 group B member 2 | RAR-beta | RARB_MOUSE | Rarb |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53344.93 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_195641 |
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| Residue: | 482 |
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| Sequence: | MSTSSHACPVPAVRGHMTHYPAAPYPLLFPPVIRGLSLPPLHGLHGHPPPSGCSTPSPAS
VGQACQRTTGGSQFAASTKWTPSLNAAIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQD
KSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGM
SKESVRNDRNKKKKEPSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSS
ADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRI
CTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAIC
LICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAE
RVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSSGNIAEHSPSVSPSSVENSGVSQSPL
LQ
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| BDBM50031458 |
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| n/a |
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| Name | BDBM50031458 |
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| Synonyms: | (2Z,5E)-7-Methyl-3-[(E)-2-(2,6,6-trimethyl-cyclohex-1-enyl)-vinyl]-nona-2,5-dienoic acid | CHEMBL75548 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H32O2 |
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| Mol. Mass. | 316.4776 |
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| SMILES | CCC(C)\C=C\C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C(O)=O |c:10| |
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| Structure | 
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