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TargetHistamine H3 receptor
LigandBDBM50034706
Substrate/Competitorn/a
Meas. Tech.ChEMBL_85848 (CHEMBL693575)
Ki 11±n/a nM
Citation Shih, NYLupo, ATAslanian, ROrlando, SPiwinski, JJGreen, MJGanguly, AKClark, MATozzi, SKreutner, W A novel pyrrolidine analog of histamine as a potent, highly selective histamine H3 receptor agonist. J Med Chem38:1593-9 (1995) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Histamine H3 receptor
Name:Histamine H3 receptor
Synonyms:HISTAMINE H3 | HRH3 | HRH3_CAVPO | Histamine H3 receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:48753.61
Organism:GUINEA PIG
Description:HISTAMINE H3 HRH3 GUINEA PIG::Q9JI35
Residue:445
Sequence:
MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAF
VADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCT
SSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSG
GSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGARE
AGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHSSLEHCWK
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  Blast E-value cutoff:
BDBM50034706
n/a
NameBDBM50034706
Synonyms:(1R,2R)-2-(1H-Imidazol-4-yl)-1-methyl-propylamine | CHEMBL40378
TypeSmall organic molecule
Emp. Form.C7H13N3
Mol. Mass.139.1982
SMILESC[C@@H](N)[C@@H](C)c1cnc[nH]1
Structure
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