| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase |
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| Ligand | BDBM50489423 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_935175 (CHEMBL2317337) |
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| IC50 | 1.000000±n/a nM |
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| Citation |  Feng, E; Shin, WJ; Zhu, X; Li, J; Ye, D; Wang, J; Zheng, M; Zuo, JP; No, KT; Liu, X; Zhu, W; Tang, W; Seong, BL; Jiang, H; Liu, H Structure-based design and synthesis of C-1- and C-4-modified analogs of zanamivir as neuraminidase inhibitors. J Med Chem56:671-84 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuraminidase |
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| Name: | Neuraminidase |
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| Synonyms: | NA | NRAM_I33A0 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49687.56 |
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| Organism: | Influenza A virus |
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| Description: | ChEMBL_1347422 |
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| Residue: | 453 |
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| Sequence: | MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGIITYNVVA
GQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQ
GALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGIS
GPDNGAVAVLKYNGIITETIKSWRKKILRTQESECTCVNGSCFTIMTDGPSNGLASYKIF
KIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGY
ICSGVFGDNPRPKDGPGSCGPVSADGANGVKGFSYRYGNGVWIGRTKSDSSRHGFEMIWD
PNGWTETDSRFSVRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPEEETI
WTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
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| BDBM50489423 |
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| n/a |
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| Name | BDBM50489423 |
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| Synonyms: | CHEMBL2315323 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H26FN5O6 |
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| Mol. Mass. | 439.438 |
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| SMILES | [H][C@]1(OC(=C[C@H](NC(N)=N)[C@H]1NC(C)=O)C(=O)NCc1cccc(F)c1)[C@H](O)[C@H](O)CO |r,c:3| |
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| Structure | 
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