| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50490655 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_949008 (CHEMBL2342760) |
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| Ki | >100000±n/a nM |
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| Citation |  Novikov, MS; Valuev-Elliston, VT; Babkov, DA; Paramonova, MP; Ivanov, AV; Gavryushov, SA; Khandazhinskaya, AL; Kochetkov, SN; Pannecouque, C; Andrei, G; Snoeck, R; Balzarini, J; Seley-Radtke, KL N1,N3-disubstituted uracils as nonnucleoside inhibitors of HIV-1 reverse transcriptase. Bioorg Med Chem21:1150-8 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM50490655 |
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| n/a |
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| Name | BDBM50490655 |
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| Synonyms: | CHEMBL2337199 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20N2O3 |
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| Mol. Mass. | 336.3844 |
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| SMILES | Cc1ccccc1OCCn1ccc(=O)n(Cc2ccccc2)c1=O |
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| Structure | 
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