| Reaction Details |
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 | Report a problem with these data |
| Target | Protein kinase C delta type |
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| Ligand | BDBM50491400 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_959553 (CHEMBL2384827) |
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| Ki | 1.3±n/a nM |
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| Citation |  Kamachi, H; Tanaka, K; Yanagita, RC; Murakami, A; Murakami, K; Tokuda, H; Suzuki, N; Nakagawa, Y; Irie, K Structure-activity studies on the side chain of a simplified analog of aplysiatoxin (aplog-1) with anti-proliferative activity. Bioorg Med Chem21:2695-702 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein kinase C delta type |
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| Name: | Protein kinase C delta type |
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| Synonyms: | KPCD_HUMAN | PKC delta | PKCD | PRKCD | Protein Kinase C- delta | Protein kinase C, PKC; classical/novel | nPKC-delta |
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| Type: | Enzyme |
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| Mol. Mass.: | 77516.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | The recombinant human PKC enzymes were
produced using a baculovirus expression system in SF9 cells |
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| Residue: | 676 |
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| Sequence: | MAPFLRIAFNSYELGSLQAEDEANQPFCAVKMKEALSTERGKTLVQKKPTMYPEWKSTFD
AHIYEGRVIQIVLMRAAEEPVSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMSVQY
FLEDVDCKQSMRSEDEAKFPTMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKDFVW
GLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTAANSRDTIFQKERFNIDMPHRFKVHNYMS
PTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCGINQKLLAEALNQVTQRASR
RSDSASSEPVGIYQGFEKKTGVAGEDMQDNSGTYGKIWEGSSKCNINNFIFHKVLGKGSF
GKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVLTLAAENPFLTHLICTFQTK
DHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGIIYRDLKLDNVL
LDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYE
MLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFEREPTKRLGVTGNIKIH
PFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQEFLNEKARLSYSDKNLIDSMDQSAF
AGFSFVNPKFEHLLED
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| BDBM50491400 |
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| n/a |
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| Name | BDBM50491400 |
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| Synonyms: | CHEMBL2381165 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H37IO8 |
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| Mol. Mass. | 616.4824 |
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| SMILES | [H][C@@]12CCC(C)(C)[C@]3(C[C@@]([H])(C[C@@H](CCCCc4ccc(I)c(O)c4)O3)OC(=O)C[C@H](CO)OC(=O)C1)O2 |r| |
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| Structure | 
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