| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Matrix protein 2 [1-96] |
|---|
| Ligand | BDBM50033369 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1275615 (CHEMBL3090746) |
|---|
| IC50 | 199900±n/a nM |
|---|
| Citation |  Rey-Carrizo, M; Torres, E; Ma, C; Barniol-Xicota, M; Wang, J; Wu, Y; Naesens, L; DeGrado, WF; Lamb, RA; Pinto, LH; Vázquez, S 3-Azatetracyclo[5.2.1.1(5,8).0(1,5)]undecane derivatives: from wild-type inhibitors of the M2 ion channel of influenza A virus to derivatives with potent activity against the V27A mutant. J Med Chem56:9265-74 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Matrix protein 2 [1-96] |
|---|
| Name: | Matrix protein 2 [1-96] |
|---|
| Synonyms: | M | M2_I72A2 | Matrix protein 2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 11051.96 |
|---|
| Organism: | Influenza A virus |
|---|
| Description: | ChEMBL_1453980 |
|---|
| Residue: | 96 |
|---|
| Sequence: | MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLK
RGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIEL
|
|
|
|---|
| BDBM50033369 |
|---|
| n/a |
|---|
| Name | BDBM50033369 |
|---|
| Synonyms: | AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H17N |
|---|
| Mol. Mass. | 151.2487 |
|---|
| SMILES | NC12CC3CC(CC(C3)C1)C2 |THB:6:5:2:8.7.9,6:7:4.5.10:2,9:7:4:10.1.2,9:1:4:8.6.7,0:1:4:8.6.7| |
|---|
| Structure | 
|
|---|
Search and Browse
