| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50045748 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_220932 (CHEMBL874095) |
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| Ki | 54±n/a nM |
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| Citation |  Zimmerman, DM; Leander, JD; Cantrell, BE; Reel, JK; Snoddy, J; Mendelsohn, LG; Johnson, BG; Mitch, CH Structure-activity relationships of trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine antagonists for mu- and kappa-opioid receptors. J Med Chem36:2833-41 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42744.99 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | P41144 |
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| Residue: | 380 |
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| Sequence: | MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
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| BDBM50045748 |
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| n/a |
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| Name | BDBM50045748 |
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| Synonyms: | 3-{1-[2-(3-Chloro-phenyl)-ethyl]-3,4-dimethyl-piperidin-4-yl}-phenol | CHEMBL97767 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26ClNO |
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| Mol. Mass. | 343.89 |
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| SMILES | C[C@H]1CN(CCc2cccc(Cl)c2)CC[C@@]1(C)c1cccc(O)c1 |
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| Structure | 
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