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TargetNociceptin/mu opioid receptor
LigandBDBM50045779
Substrate/Competitorn/a
Meas. Tech.ChEBML_220391
Ki 0.290000±n/a nM
Citation Mitch CHLeander JDMendelsohn LGShaw WNWong DTCantrell BEJohnson BGReel JKSnoddy JDTakemori AE 3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines: opioid antagonists with potent anorectant activity. J Med Chem 36:2842-50 (1993) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Nociceptin/mu opioid receptor
Name:Nociceptin/mu opioid receptor
Synonyms:MOR-1 | MUOR1 | Mu-type opioid receptor | Mu-type opioid receptor (MOR) | OPIATE Mu | Opiate non-selective | Opioid receptor B
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44503.11
Organism:Rattus norvegicus (rat)
Description:Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor.
Residue:398
Sequence:
MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50045779
n/a
NameBDBM50045779
Synonyms:3-[3,4-Dimethyl-1-(4-methyl-pentyl)-piperidin-4-yl]-phenol | CHEMBL97223
TypeSmall organic molecule
Emp. Form.C19H31NO
Mol. Mass.289.4555
SMILESCC(C)CCCN1CC[C@](C)([C@@H](C)C1)c1cccc(O)c1
Structure
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