| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Gastrin/cholecystokinin type B receptor |
|---|
| Ligand | BDBM50045797 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_49880 |
|---|
| Ki | >0.000100±n/a nM |
|---|
| Citation |  Blommaert, AG; Weng, JH; Dorville, A; McCort, I; Ducos, B; Durieux, C; Roques, BP Cholecystokinin peptidomimetics as selective CCK-B antagonists: design, synthesis, and in vitro and in vivo biochemical properties. J Med Chem36:2868-77 (1993) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Gastrin/cholecystokinin type B receptor |
|---|
| Name: | Gastrin/cholecystokinin type B receptor |
|---|
| Synonyms: | CCK-2 receptor | CCK-B receptor | CCK-BR | CCKBR | CCKRB | Cholecystokinin A | Cholecystokinin receptor | Cholecystokinin-2 Receptor | GASR_HUMAN | Gastrin/cholecystokinin type B receptor |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 48445.79 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Stable expression of human CCK-2 receptors in HEK 293 cells. |
|---|
| Residue: | 447 |
|---|
| Sequence: | MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITL
YAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
IFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWL
LSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGL
ISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS
RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDG
PGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRAL
PDEDPPTPSIASLSRLSYTTISTLGPG
|
|
|
|---|
| BDBM50045797 |
|---|
| n/a |
|---|
| Name | BDBM50045797 |
|---|
| Synonyms: | 2-[3-(4-Chloro-phenyl)-ureido]-3-(1H-indol-3-yl)-2-methyl-N-phenethyl-propionamide | CHEMBL319096 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H27ClN4O2 |
|---|
| Mol. Mass. | 474.982 |
|---|
| SMILES | CC(Cc1c[nH]c2ccccc12)(NC(=O)Nc1ccc(Cl)cc1)C(=O)NCCc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
