| Reaction Details |
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 | Report a problem with these data |
| Target | Carnitine O-palmitoyltransferase 1, muscle isoform |
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| Ligand | BDBM50046145 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_46330 |
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| Ki | 2800±n/a nM |
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| Citation |  Gandour, RD; Leung, OT; Greway, AT; Ramsay, RR; Nic a'Bháird, N; Fronczek, FR; Bellard, BM; Kumaravel, G (+)-Hemipalmitoylcarnitinium strongly inhibits carnitine palmitoyltransferase-I in intact mitochondria. J Med Chem36:237-42 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Carnitine O-palmitoyltransferase 1, muscle isoform |
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| Name: | Carnitine O-palmitoyltransferase 1, muscle isoform |
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| Synonyms: | CPT1B_RAT | Carnitine palmitoyltransferase 1B | Cpt1b |
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| Type: | PROTEIN |
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| Mol. Mass.: | 88241.28 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_887447 |
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| Residue: | 772 |
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| Sequence: | MAEAHQAVAFQFTVTPDGVDFRLSREALRHIYLSGINSWKKRLIRIKNGILRGVYPGSPT
SWLVVVMATVGSNYCKVDISMGLVHCIQRCLPTRYGSYGTPQTETLLSMVIFSTGVWATG
IFLFRQTLKLLLSYHGWMFEMHSKTSHATKIWAICVRLLSSRRPMLYSFQTSLPKLPVPS
VPATIHRYLDSVRPLLDDEAYFRMESLAKEFQDKIAPRLQKYLVLKSWWATNYVSDWWEE
YVYLRGRSPIMVNSNYYAMDFVLIKNTSQQAARLGNTVHAMIMYRRKLDREEIKPVMALG
MVPMCSYQMERMFNTTRIPGKETDLLQHLSESRHVAVYHKGRFFKVWLYEGSCLLKPRDL
EMQFQRILDDTSPPQPGEEKLAALTAGGRVEWAEARQKFFSSGKNKMSLDTIERAAFFVA
LDEDSHCYNPDDEASLSLYGKSLLHGNCYNRWFDKSFTLISCKNGQLGLNTEHSWADAPI
IGHLWEFVLATDTFHLGYTETGHCVGEPNTKLPPPQRMQWDIPEQCQTAIENSYQVAKAL
ADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDKGKFCLTYEASMTRMFREG
RTETVRSCTSESTAFVRAMMTGSHKKQDLQDLFRKASEKHQNMYRLAMTGAGIDRHLFCL
YIVSKYLGVRSPFLDEVLSEPWSLSTSQIPQFQICMFDPKQYPNHLGAGGGFGPVADHGY
GVSYMIAGENTMFFHVSSKLSSSETNALRFGNHIRQALLDIADLFKISKTDS
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| BDBM50046145 |
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| n/a |
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| Name | BDBM50046145 |
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| Synonyms: | 2-[6-hydroxy-4,4-dimethyl-6-pentadecyl-(2R,6S)-1,4-oxazinan-4-ium-2-yl]acetate(hemipalmitoylcarnitinium (HPC)) | Acylcarnitine analogue | CHEMBL48257 | Hemiacylcarnitinium(+)-HPC |
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| Type | Small organic molecule |
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| Emp. Form. | C23H45NO4 |
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| Mol. Mass. | 399.6077 |
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| SMILES | CCCCCCCCCCCCCCC[C@@]1(O)C[N+](C)(C)C[C@@H](CC([O-])=O)O1 |
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| Structure | 
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