| Reaction Details |
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 | Report a problem with these data |
| Target | Laforin |
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| Ligand | BDBM50498446 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1506353 (CHEMBL3599432) |
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| IC50 | 56000±n/a nM |
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| Citation |  He, R; Bai, Y; Yu, ZH; Wu, L; Gunawan, AM; Zhang, ZY Diversity-Oriented Synthesis for Novel, Selective and Drug-like Inhibitors for a Phosphatase from Mycobacterium Tuberculosis. Medchemcomm5:1496-1499 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Laforin |
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| Name: | Laforin |
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| Synonyms: | EPM2A | EPM2A_HUMAN | LAFPTPase | Lafora PTPase | Laforin |
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| Type: | Protein |
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| Mol. Mass.: | 37158.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O95278 |
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| Residue: | 331 |
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| Sequence: | MRFRFGVVVPPAVAGARPELLVVGSRPELGRWEPRGAVRLRPAGTAAGDGALALQEPGLW
LGEVELAAEEAAQDGAEPGRVDTFWYKFLKREPGGELSWEGNGPHHDRCCTYNENNLVDG
VYCLPIGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQVEHVTIKL
KHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTMIKLYREEGLAYIWMPTPDMSTEG
RVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWLQYVMGWNLRKVQYFLMAKR
PAVYIDEEALARAQEDFFQKFGKVRSSVCSL
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| BDBM50498446 |
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| n/a |
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| Name | BDBM50498446 |
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| Synonyms: | CHEMBL3596431 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H9BrN2O3S |
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| Mol. Mass. | 365.202 |
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| SMILES | OC(=O)c1cc2sc(Nc3cccc(Br)c3)nc2cc1O |
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| Structure | 
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