| Reaction Details |
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 | Report a problem with these data |
| Target | Cholecystokinin receptor type A |
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| Ligand | BDBM50454480 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_50056 (CHEMBL662425) |
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| IC50 | 400±n/a nM |
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| Citation |  Castro, JL; Ball, RG; Broughton, HB; Russell, MG; Rathbone, D; Watt, AP; Baker, R; Chapman, KL; Fletcher, AE; Patel, S; Smith, AJ; Marshall, GR; Ryecroft, W; Matassa, VG Controlled modification of acidity in cholecystokinin B receptor antagonists: N-(1,4-benzodiazepin-3-yl)-N'-[3-(tetrazol-5-ylamino) phenyl]ureas. J Med Chem39:842-9 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholecystokinin receptor type A |
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| Name: | Cholecystokinin receptor type A |
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| Synonyms: | CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49676.37 |
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| Organism: | RAT |
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| Description: | Cholecystokinin central 0 RAT::P30551 |
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| Residue: | 444 |
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| Sequence: | MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQI
LLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLK
DFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAAT
WCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVM
VVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQL
SSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAE
KHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEE
DGRTIRALLSRYSYSHMSTSAPPP
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| BDBM50454480 |
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| n/a |
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| Name | BDBM50454480 |
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| Synonyms: | CHEMBL2093059 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29N9O2 |
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| Mol. Mass. | 487.5569 |
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| SMILES | CN(c1nn[nH]n1)c1cccc(NC(=O)N[C@@H]2N=C(C3CCCCC3)c3ccccc3N(C)C2=O)c1 |t:18| |
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| Structure | 
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