Reaction Details |
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Target | Mu-type opioid receptor |
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Ligand | BDBM50500611 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1548303 (CHEMBL3755754) |
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IC50 | 95±n/a nM |
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Citation | Deekonda, S; Cole, J; Sunna, S; Rankin, D; Largent-Milnes, TM; Davis, P; BassiriRad, NM; Lai, J; Vanderah, TW; Porecca, F; Hruby, VJ Enkephalin analogues with N-phenyl-N-(piperidin-2-ylmethyl)propionamide derivatives: Synthesis and biological evaluations. Bioorg Med Chem Lett26:222-7 (2016) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Mu-type opioid receptor |
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Name: | Mu-type opioid receptor |
Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 11165.58 |
Organism: | GUINEA PIG |
Description: | P97266 |
Residue: | 98 |
Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
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BDBM50500611 |
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n/a |
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Name | BDBM50500611 |
Synonyms: | CHEMBL4299482 |
Type | Small organic molecule |
Emp. Form. | C49H60N6O7 |
Mol. Mass. | 845.0367 |
SMILES | CCC(=O)N(CC1CCCCN1Cc1ccc2[C@@H](CCCc2c1)N[C@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)c1ccccc1 |r| |
Structure |
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