| Reaction Details |
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 | Report a problem with these data |
| Target | Anionic trypsin |
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| Ligand | BDBM50054483 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_212174 (CHEMBL815149) |
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| IC50 | 113±n/a nM |
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| Citation |  Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF Potent and selective thrombin inhibitors incorporating the constrained arginine mimic l-3-piperidyl(N-guanidino)alanine at P1. J Med Chem39:4527-30 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Anionic trypsin |
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| Name: | Anionic trypsin |
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| Synonyms: | Anionic trypsin | TRY2_BOVIN | Trypsin II |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26281.39 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_212177 |
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| Residue: | 247 |
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| Sequence: | MHPLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVS
AAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVIN
ARVSTLLLPSACASAGTECLISGWGNTLSSGVNYPDLLQCLVAPLLSHADCEASYPGQIT
NNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQ
ETIAANS
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| BDBM50054483 |
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| n/a |
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| Name | BDBM50054483 |
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| Synonyms: | (S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-ethylcarbamoyl]-pyrrolidin-1-yl}-4-oxo-3-(2-propyl-pentanoylamino)-butyric acid methyl ester | CHEMBL342838 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H46N6O6 |
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| Mol. Mass. | 550.6907 |
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| SMILES | CCCC(CCC)C(=O)N[C@@H](CC(=O)OC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1CCCN(C1)C(N)=N)C=O |
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| Structure | 
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