| Reaction Details |
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 | Report a problem with these data |
| Target | Anionic trypsin |
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| Ligand | BDBM50054484 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_212174 (CHEMBL815149) |
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| IC50 | 329±n/a nM |
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| Citation |  Levy, OE; Semple, JE; Lim, ML; Reiner, J; Rote, WE; Dempsey, E; Richard, BM; Zhang, E; Tulinsky, A; Ripka, WC; Nutt, RF Potent and selective thrombin inhibitors incorporating the constrained arginine mimic l-3-piperidyl(N-guanidino)alanine at P1. J Med Chem39:4527-30 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Anionic trypsin |
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| Name: | Anionic trypsin |
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| Synonyms: | Anionic trypsin | TRY2_BOVIN | Trypsin II |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26281.39 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_212177 |
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| Residue: | 247 |
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| Sequence: | MHPLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVS
AAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVIN
ARVSTLLLPSACASAGTECLISGWGNTLSSGVNYPDLLQCLVAPLLSHADCEASYPGQIT
NNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQ
ETIAANS
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| BDBM50054484 |
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| n/a |
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| Name | BDBM50054484 |
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| Synonyms: | CHEMBL344204 | CVS-1778 | N-((S)-1-Formyl-4-guanidino-butyl)-2-((S)-2-oxo-3-phenylmethanesulfonylamino-azepan-1-yl)-acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C21H32N6O5S |
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| Mol. Mass. | 480.581 |
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| SMILES | NC(=N)NCCC[C@H](NC(=O)CN1CCCC[C@H](NS(=O)(=O)Cc2ccccc2)C1=O)C=O |
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| Structure | 
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