| Reaction Details |
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 | Report a problem with these data |
| Target | Pirin |
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| Ligand | BDBM50029085 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1830006 (CHEMBL4329880) |
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| IC50 | >10000±n/a nM |
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| Citation |  Meyers, J; Chessum, NEA; Ali, S; Mok, NY; Wilding, B; Pasqua, AE; Rowlands, M; Tucker, MJ; Evans, LE; Rye, CS; O'Fee, L; Le Bihan, YV; Burke, R; Carter, M; Workman, P; Blagg, J; Brown, N; van Montfort, RLM; Jones, K; Cheeseman, MD Privileged Structures and Polypharmacology within and between Protein Families. ACS Med Chem Lett9:1199-1204 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pirin |
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| Name: | Pirin |
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| Synonyms: | PIR | PIR_HUMAN | Probable quercetin 2,3-dioxygenase PIR | Probable quercetinase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32115.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_811273 |
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| Residue: | 290 |
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| Sequence: | MGSSKKVTLSVLSREQSEGVGARVRRSIGRPELKNLDPFLLFDEFKGGRPGGFPDHPHRG
FETVSYLLEGGSMAHEDFCGHTGKMNPGDLQWMTAGRGILHAEMPCSEEPAHGLQLWVNL
RSSEKMVEPQYQELKSEEIPKPSKDGVTVAVISGEALGIKSKVYTRTPTLYLDFKLDPGA
KHSQPIPKGWTSFIYTISGDVYIGPDDAQQKIEPHHTAVLGEGDSVQVENKDPKRSHFVL
IAGEPLREPVIQHGPFVMNTNEEISQAILDFRNAKNGFERAKTWKSKIGN
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| BDBM50029085 |
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| n/a |
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| Name | BDBM50029085 |
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| Synonyms: | CHEBI:83405 | CHEMBL525191 | GDC-0879 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18N4O2 |
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| Mol. Mass. | 334.3718 |
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| SMILES | OCCn1cc(c(n1)-c1ccncc1)-c1ccc2\C(CCc2c1)=N\O |
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| Structure | 
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