| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM50067887 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_35526 (CHEMBL649552) |
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| IC50 | 5000±n/a nM |
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| Citation |  Weston, GS; Blázquez, J; Baquero, F; Shoichet, BK Structure-based enhancement of boronic acid-based inhibitors of AmpC beta-lactamase. J Med Chem41:4577-86 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC |
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| Type: | Protien |
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| Mol. Mass.: | 41561.62 |
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| Organism: | Escherichia coli |
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| Description: | P00811 |
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| Residue: | 377 |
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| Sequence: | MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWG
YADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGI
TLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVK
PSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVK
STIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSII
NGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNY
PNPARVDAAWQILNALQ
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| BDBM50067887 |
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| n/a |
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| Name | BDBM50067887 |
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| Synonyms: | 3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihydroxyborane | 3-Nitrophenyl boronic acid | Boronic acid derivative | CHEMBL20945 | m-nitophenyl boronic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C6H6BNO4 |
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| Mol. Mass. | 166.927 |
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| SMILES | O[B-](=[OH+])c1cccc(c1)[N+]([O-])=O |
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| Structure | 
|
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