| Reaction Details |
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 | Report a problem with these data |
| Target | Similar to alpha-tubulin isoform 1 |
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| Ligand | BDBM50513148 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1852096 (CHEMBL4352720) |
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| IC50 | 3800±n/a nM |
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| Citation |  Niu, H; Strecker, TE; Gerberich, JL; Campbell, JW; Saha, D; Mondal, D; Hamel, E; Chaplin, DJ; Mason, RP; Trawick, ML; Pinney, KG Structure Guided Design, Synthesis, and Biological Evaluation of Novel Benzosuberene Analogues as Inhibitors of Tubulin Polymerization. J Med Chem62:5594-5615 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Similar to alpha-tubulin isoform 1 |
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| Name: | Similar to alpha-tubulin isoform 1 |
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| Synonyms: | Similar to alpha-tubulin isoform 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 10383.05 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_104716 |
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| Residue: | 99 |
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| Sequence: | CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
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| BDBM50513148 |
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| n/a |
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| Name | BDBM50513148 |
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| Synonyms: | CHEMBL4469445 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H26O6 |
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| Mol. Mass. | 386.4382 |
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| SMILES | COc1ccc2c(CCC(O)C=C2c2cc(OC)c(OC)c(OC)c2)c1OC |c:11| |
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| Structure | 
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