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TargetOxysterols receptor LXR-beta
LigandBDBM23448
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1859653 (CHEMBL4360509)
Ki 66000±n/a nM
Citation Zhang, ZChen, HChen, ZDing, PJu, YGu, QXu, JZhou, H Identify liver X receptor ? modulator building blocks by developing a fluorescence polarization-based competition assay. Eur J Med Chem178:458-467 (2019) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Oxysterols receptor LXR-beta
Name:Oxysterols receptor LXR-beta
Synonyms:LXRB | Liver X receptor beta (NR1H2) | Liver X, LXR beta | NER | NR1H2 | NR1H2_HUMAN | Nuclear receptor NER | UNR | Ubiquitously-expressed nuclear receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:50978.79
Organism:Homo sapiens (Human)
Description:P55055
Residue:460
Sequence:
MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDW
VIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGA
RRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQ
SQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKR
SFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQI
ALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMR
RLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRM
LMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
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  Blast E-value cutoff:
BDBM23448
n/a
NameBDBM23448
Synonyms:BUTYLPARABEN | Butyl paraben | Nipabutyl | butyl 4-hydroxybenzoate | cid_7184
TypeSmall organic molecule
Emp. Form.C11H14O3
Mol. Mass.194.2271
SMILESCCCCOC(=O)c1ccc(O)cc1
Structure
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