| Reaction Details |
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 | Report a problem with these data |
| Target | Cholesteryl ester transfer protein |
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| Ligand | BDBM50070315 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_49089 |
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| IC50 | 300±n/a nM |
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| Citation |  Hegde, VR; Dai, P; Patel, M; Das, PR; Wang, S; Puar, MS A depsipeptide fungal metabolite inhibitor of cholesteryl ester transfer protein. Bioorg Med Chem Lett8:1277-80 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholesteryl ester transfer protein |
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| Name: | Cholesteryl ester transfer protein |
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| Synonyms: | CETP | CETP_HUMAN | Cholesteryl ester transfer protein (CETP) | Lipid transfer protein I |
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| Type: | Enzyme |
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| Mol. Mass.: | 54751.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11597 |
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| Residue: | 493 |
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| Sequence: | MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDI
TGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTT
AWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWI
KQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVI
TASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRL
MLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSS
VMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSE
SVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGF
PEHLLVDFLQSLS
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| BDBM50070315 |
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| n/a |
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| Name | BDBM50070315 |
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| Synonyms: | (3S,9S)-9-Benzyl-3-isobutyl-6-methyl-13-(1-methyl-pentyl)-1-oxa-4,7,10-triaza-cyclotridecane-2,5,8,11-tetraone | CHEMBL2371731 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H41N3O5 |
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| Mol. Mass. | 487.6315 |
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| SMILES | CCCCC(C)C1CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)O1 |
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| Structure | 
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