BindingDB PrimarySearch

Found 26 hits with Last Name = 'das' and Initial = 'pr'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50292438 (1,-(4-amino-5-oxotridecane-1,13-diyl)diguanidine \|...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of QNB from muscarinic M2 receptor				J Nat Prod 58: 843-847 (1995) Article DOI: 10.1021/np50120a004 BindingDB Entry DOI: 10.7270/Q2FJ2GS1
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50292438 (1,-(4-amino-5-oxotridecane-1,13-diyl)diguanidine \|...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of QNB from muscarinic M1 receptor				J Nat Prod 58: 843-847 (1995) Article DOI: 10.1021/np50120a004 BindingDB Entry DOI: 10.7270/Q2FJ2GS1
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50292438 (1,-(4-amino-5-oxotridecane-1,13-diyl)diguanidine \|...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of QNB from muscarinic M4 receptor				J Nat Prod 58: 843-847 (1995) Article DOI: 10.1021/np50120a004 BindingDB Entry DOI: 10.7270/Q2FJ2GS1
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50197834 (2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...) Show SMILES COc1c(O)cc2C(=O)Nc3cc4ccc(O)cc4c1c23 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of CDK2				Bioorg Med Chem Lett 20: 1344-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.018 BindingDB Entry DOI: 10.7270/Q2BZ664X
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50197834 (2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...) Show SMILES COc1c(O)cc2C(=O)Nc3cc4ccc(O)cc4c1c23 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	214	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of CDC2				Bioorg Med Chem Lett 20: 1344-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.018 BindingDB Entry DOI: 10.7270/Q2BZ664X
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus)	BDBM50135740 (2,3,4,5,6,7,14,15-octahydroxy-13-(5-hydroxy-4-oxo-...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of the compound evaluated in the HCV NS3 protease activity assay				Bioorg Med Chem Lett 13: 2925-8 (2003) BindingDB Entry DOI: 10.7270/Q2HX1C2D
Schering-Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50070315 ((3S,9S)-9-Benzyl-3-isobutyl-6-methyl-13-(1-methyl-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Compound was evaluated for inhibitory activity against cholesteryl ester transfer protein				Bioorg Med Chem Lett 8: 1277-80 (1999) BindingDB Entry DOI: 10.7270/Q25X282F
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus)	BDBM50135739 (13-[3,5-dihydroxy-4-(3-phenylpropanoyl)phenoxy]-2,...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of the compound evaluated in the HCV NS3 protease assay				Bioorg Med Chem Lett 13: 2925-8 (2003) BindingDB Entry DOI: 10.7270/Q2HX1C2D
Schering-Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50292439 (CHEMBL479224 \| N-(1,13-diguanidino-5-oxotridecan-4...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of QNB from muscarinic M4 receptor				J Nat Prod 58: 843-847 (1995) Article DOI: 10.1021/np50120a004 BindingDB Entry DOI: 10.7270/Q2FJ2GS1
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50292439 (CHEMBL479224 \| N-(1,13-diguanidino-5-oxotridecan-4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of QNB from muscarinic M2 receptor				J Nat Prod 58: 843-847 (1995) Article DOI: 10.1021/np50120a004 BindingDB Entry DOI: 10.7270/Q2FJ2GS1
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50292439 (CHEMBL479224 \| N-(1,13-diguanidino-5-oxotridecan-4...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of QNB from muscarinic M1 receptor				J Nat Prod 58: 843-847 (1995) Article DOI: 10.1021/np50120a004 BindingDB Entry DOI: 10.7270/Q2FJ2GS1
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM50197834 (2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...) Show SMILES COc1c(O)cc2C(=O)Nc3cc4ccc(O)cc4c1c23 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of CDK4				Bioorg Med Chem Lett 20: 1344-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.018 BindingDB Entry DOI: 10.7270/Q2BZ664X
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50197834 (2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...) Show SMILES COc1c(O)cc2C(=O)Nc3cc4ccc(O)cc4c1c23 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Aurora 2 kinase				Bioorg Med Chem Lett 20: 1344-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.018 BindingDB Entry DOI: 10.7270/Q2BZ664X
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus B)	BDBM50135740 (2,3,4,5,6,7,14,15-octahydroxy-13-(5-hydroxy-4-oxo-...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of the compound evaluated in the HCV protease binding assay				Bioorg Med Chem Lett 13: 2925-8 (2003) BindingDB Entry DOI: 10.7270/Q2HX1C2D
Schering-Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50153762 (3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of MIP-1beta ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assay				Bioorg Med Chem Lett 14: 5339-42 (2004) Article DOI: 10.1016/j.bmcl.2004.08.021 BindingDB Entry DOI: 10.7270/Q2SJ1K31
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50153762 (3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of MIP-1beta ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assay				Bioorg Med Chem Lett 14: 5339-42 (2004) Article DOI: 10.1016/j.bmcl.2004.08.021 BindingDB Entry DOI: 10.7270/Q2SJ1K31
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50153764 ((Z)-1-((1S,2S)-2-((S)-hydroxy((R)-6-oxo-3,6-dihydr...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of MIP-1beta ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assay				Bioorg Med Chem Lett 14: 5339-42 (2004) Article DOI: 10.1016/j.bmcl.2004.08.021 BindingDB Entry DOI: 10.7270/Q2SJ1K31
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50153762 (3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of 50% of RANTES co-receptor of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assay				Bioorg Med Chem Lett 14: 5339-42 (2004) Article DOI: 10.1016/j.bmcl.2004.08.021 BindingDB Entry DOI: 10.7270/Q2SJ1K31
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50153762 (3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of MIP-1alpha ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assay				Bioorg Med Chem Lett 14: 5339-42 (2004) Article DOI: 10.1016/j.bmcl.2004.08.021 BindingDB Entry DOI: 10.7270/Q2SJ1K31
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50153762 (3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of RANTES co-receptor of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assay				Bioorg Med Chem Lett 14: 5339-42 (2004) Article DOI: 10.1016/j.bmcl.2004.08.021 BindingDB Entry DOI: 10.7270/Q2SJ1K31
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50153764 ((Z)-1-((1S,2S)-2-((S)-hydroxy((R)-6-oxo-3,6-dihydr...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of MIP-1alpha ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assay				Bioorg Med Chem Lett 14: 5339-42 (2004) Article DOI: 10.1016/j.bmcl.2004.08.021 BindingDB Entry DOI: 10.7270/Q2SJ1K31
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50153762 (3-(4-Methoxy-phenyl)-acrylic acid 2-{(1S,2S)-2-[(S...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of MIP-1alpha ligand of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assay				Bioorg Med Chem Lett 14: 5339-42 (2004) Article DOI: 10.1016/j.bmcl.2004.08.021 BindingDB Entry DOI: 10.7270/Q2SJ1K31
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50153764 ((Z)-1-((1S,2S)-2-((S)-hydroxy((R)-6-oxo-3,6-dihydr...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of RANTES co-receptor of chemokine receptor 5 induced calcium signal in U-87-CCR5 cells by calcium mobilization assay				Bioorg Med Chem Lett 14: 5339-42 (2004) Article DOI: 10.1016/j.bmcl.2004.08.021 BindingDB Entry DOI: 10.7270/Q2SJ1K31
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50306911 (8-((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-hydroxymeth...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of CDK2				Bioorg Med Chem Lett 20: 1344-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.018 BindingDB Entry DOI: 10.7270/Q2BZ664X
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50070315 ((3S,9S)-9-Benzyl-3-isobutyl-6-methyl-13-(1-methyl-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Tested for inhibition of substrate hydrolysis in the presence of porcine kidney esterase at a concentration of 45 nM				Bioorg Med Chem Lett 8: 1277-80 (1999) BindingDB Entry DOI: 10.7270/Q25X282F
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50070315 ((3S,9S)-9-Benzyl-3-isobutyl-6-methyl-13-(1-methyl-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description pA2 value towards endothelin receptor A was determined as functional ETA antagonism				Bioorg Med Chem Lett 8: 1277-80 (1999) BindingDB Entry DOI: 10.7270/Q25X282F
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair