| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 14 |
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| Ligand | BDBM50515478 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1861162 (CHEMBL4362018) |
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| IC50 | 4.5±n/a nM |
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| Citation |  Zhang, Z; Hao, K; Li, H; Lu, R; Liu, C; Zhou, M; Li, B; Meng, Z; Hu, Q; Jiang, C Design, synthesis and anti-inflammatory evaluation of 3-amide benzoic acid derivatives as novel P2Y Eur J Med Chem181:0 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 14 |
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| Name: | P2Y purinoceptor 14 |
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| Synonyms: | GPR105 | Insulin Receptor-Related Protein (INSRR) | KIAA0001 | P2RY14 | P2Y14_HUMAN | Purinergic receptor P2Y14 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38991.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1502487 |
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| Residue: | 338 |
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| Sequence: | MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYL
KNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRY
YKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELG
RKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVF
VFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQ
PFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
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| BDBM50515478 |
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| n/a |
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| Name | BDBM50515478 |
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| Synonyms: | CHEMBL4455311 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H23N3O3 |
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| Mol. Mass. | 425.4791 |
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| SMILES | OC(=O)c1cc(NC(=O)c2ccc(cc2)C#N)cc(c1)-c1ccc(cc1)C1CCNCC1 |
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| Structure | 
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