| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50071340 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_85850 (CHEMBL693577) |
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| Ki | 5.5±n/a nM |
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| Citation |  Wolin, R; Connolly, M; Afonso, A; Hey, JA; She, H; Rivelli, MA; Willams, SM; West, RE Novel H3 receptor antagonists. Sulfonamide homologs of histamine. Bioorg Med Chem Lett8:2157-62 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HISTAMINE H3 | HRH3 | HRH3_CAVPO | Histamine H3 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48753.61 |
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| Organism: | GUINEA PIG |
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| Description: | HISTAMINE H3 HRH3 GUINEA PIG::Q9JI35 |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAF
VADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCT
SSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSG
GSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGARE
AGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHSSLEHCWK
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| BDBM50071340 |
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| n/a |
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| Name | BDBM50071340 |
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| Synonyms: | CHEMBL68336 | N-[5-(1H-Imidazol-4-yl)-pentyl]-4-nitro-benzenesulfonamide |
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| Type | Small organic molecule |
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| Emp. Form. | C14H18N4O4S |
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| Mol. Mass. | 338.382 |
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| SMILES | [O-][N+](=O)c1ccc(cc1)S(=O)(=O)NCCCCCc1cnc[nH]1 |
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| Structure | 
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