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Compile Data Set for Download or QSAR

Found 505 hits with Last Name = 'connolly' and Initial = 'm'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50052513
PNG
(8-Methyl-3-(2-oxo-propyl)-1-phenethyl-1,3,8-triaza...)
Show SMILES CN1CCC2(CC1)N(CCc1ccccc1)CN(CC(C)=O)C2=O
Show InChI InChI=1S/C19H27N3O2/c1-16(23)14-21-15-22(11-8-17-6-4-3-5-7-17)19(18(21)24)9-12-20(2)13-10-19/h3-7H,8-15H2,1-2H3
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 0.150n/an/an/an/an/an/an/an/a



Scios Nova, Inc.

Curated by ChEMBL


Assay Description
Affinity to human Bradykinin receptor B2 in CHO cell membranes determined by displacement of [3H]-NPC 17731

J Med Chem 39: 3169-73 (1996)


Article DOI: 10.1021/jm950676i
BindingDB Entry DOI: 10.7270/Q2C24VH9
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Homo sapiens (Human))		BDBM50474799
PNG
(CHEMBL416690)
Show SMILES Cc1ccc(CC2CCN(Cc3nc4cc(O)ccc4[nH]3)CC2)cc1
Show InChI InChI=1S/C21H25N3O/c1-15-2-4-16(5-3-15)12-17-8-10-24(11-9-17)14-21-22-19-7-6-18(25)13-20(19)23-21/h2-7,13,17,25H,8-12,14H2,1H3,(H,22,23)
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 0.400n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for in vitro inhibition of [3H][(E)-N-(2-methoxybenzyl)cinnamamidine binding to human NR1a/NR2B receptors expressed in LtK-cel...

J Med Chem 47: 2089-96 (2004)


Article DOI: 10.1021/jm030483s
BindingDB Entry DOI: 10.7270/Q2348P41
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50052512
PNG
(1-Cyclohexyl-8-methyl-3-(2-oxo-propyl)-1,3,8-triaz...)
Show SMILES CN1CCC2(CC1)N(CN(CC(C)=O)C2=O)C1CCCCC1
Show InChI InChI=1S/C17H29N3O2/c1-14(21)12-19-13-20(15-6-4-3-5-7-15)17(16(19)22)8-10-18(2)11-9-17/h15H,3-13H2,1-2H3
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 0.570n/an/an/an/an/an/an/an/a



Scios Nova, Inc.

Curated by ChEMBL


Assay Description
Affinity to human Bradykinin receptor B2 in CHO cell membranes determined by displacement of [3H]-NPC 17731

J Med Chem 39: 3169-73 (1996)


Article DOI: 10.1021/jm950676i
BindingDB Entry DOI: 10.7270/Q2C24VH9
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50124914
PNG
(CHEMBL161180 | N-(3,5-Dichloro-benzyl)-4-trifluoro...)
Show SMILES NC(=NCc1cc(Cl)cc(Cl)c1)c1ccc(OC(F)(F)F)cc1 |w:2.2|
Show InChI InChI=1S/C15H11Cl2F3N2O/c16-11-5-9(6-12(17)7-11)8-22-14(21)10-1-3-13(4-2-10)23-15(18,19)20/h1-7H,8H2,(H2,21,22)
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 0.600n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cells

Bioorg Med Chem Lett 13: 697-700 (2003)


BindingDB Entry DOI: 10.7270/Q2FX78TP
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Homo sapiens (Human))		BDBM50474791
PNG
(CHEMBL65693)
Show SMILES CS(=O)(=O)Nc1ccc2[nH]c(Cc3ccc(Oc4ccccc4)cc3)nc2c1
Show InChI InChI=1S/C21H19N3O3S/c1-28(25,26)24-16-9-12-19-20(14-16)23-21(22-19)13-15-7-10-18(11-8-15)27-17-5-3-2-4-6-17/h2-12,14,24H,13H2,1H3,(H,22,23)
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 0.680n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for in vitro inhibition of [3H][(E)-N-(2-methoxybenzyl)cinnamamidine binding to human NR1a/NR2B receptors expressed in LtK-cel...

J Med Chem 47: 2089-96 (2004)


Article DOI: 10.1021/jm030483s
BindingDB Entry DOI: 10.7270/Q2348P41
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50124885
PNG
((E)-N-(2-Methoxy-benzyl)-3-phenyl-acrylamidine | C...)
Show SMILES COc1ccccc1CN=C(N)C=Cc1ccccc1 |w:9.9,13.14|
Show InChI InChI=1S/C17H18N2O/c1-20-16-10-6-5-9-15(16)13-19-17(18)12-11-14-7-3-2-4-8-14/h2-12H,13H2,1H3,(H2,18,19)
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 0.700n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cells

Bioorg Med Chem Lett 13: 697-700 (2003)


BindingDB Entry DOI: 10.7270/Q2FX78TP
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Homo sapiens (Human))		BDBM50474809
PNG
(CHEMBL65454)
Show SMILES Oc1ccc2[nH]c(CN3CCC(Cc4c(F)cccc4F)CC3)nc2c1
Show InChI InChI=1S/C20H21F2N3O/c21-16-2-1-3-17(22)15(16)10-13-6-8-25(9-7-13)12-20-23-18-5-4-14(26)11-19(18)24-20/h1-5,11,13,26H,6-10,12H2,(H,23,24)
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 0.820n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for in vitro inhibition of [3H][(E)-N-(2-methoxybenzyl)cinnamamidine binding to human NR1a/NR2B receptors expressed in LtK-cel...

J Med Chem 47: 2089-96 (2004)


Article DOI: 10.1021/jm030483s
BindingDB Entry DOI: 10.7270/Q2348P41
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Homo sapiens (Human))		BDBM50474789
PNG
(CHEMBL68134)
Show SMILES Oc1ccc2[nH]c(CN3CCC(Cc4ccccc4F)CC3)nc2c1
Show InChI InChI=1S/C20H22FN3O/c21-17-4-2-1-3-15(17)11-14-7-9-24(10-8-14)13-20-22-18-6-5-16(25)12-19(18)23-20/h1-6,12,14,25H,7-11,13H2,(H,22,23)
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 0.850n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for in vitro inhibition of [3H][(E)-N-(2-methoxybenzyl)cinnamamidine binding to human NR1a/NR2B receptors expressed in LtK-cel...

J Med Chem 47: 2089-96 (2004)


Article DOI: 10.1021/jm030483s
BindingDB Entry DOI: 10.7270/Q2348P41
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Homo sapiens (Human))		BDBM50204862
PNG
(CHEMBL436521 | N-(2-((4-benzylpiperidin-1-yl)methy...)
Show SMILES CS(=O)(=O)Nc1ccc2nc(CN3CCC(Cc4ccccc4)CC3)[nH]c2c1
Show InChI InChI=1S/C21H26N4O2S/c1-28(26,27)24-18-7-8-19-20(14-18)23-21(22-19)15-25-11-9-17(10-12-25)13-16-5-3-2-4-6-16/h2-8,14,17,24H,9-13,15H2,1H3,(H,22,23)
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 0.990n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for in vitro inhibition of [3H][(E)-N-(2-methoxybenzyl)cinnamamidine binding to human NR1a/NR2B receptors expressed in LtK-cel...

J Med Chem 47: 2089-96 (2004)


Article DOI: 10.1021/jm030483s
BindingDB Entry DOI: 10.7270/Q2348P41
More data for this
Ligand-Target Pair
Peptidylprolyl isomerase


(Gallus gallus)		BDBM50068597
PNG
(1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-acetyl]-piper...)
Show SMILES COc1cc(cc(OC)c1OC)C(=O)C(=O)N1CCCCC1C(=O)OC(CCCc1ccccc1)CCCc1ccccc1
Show InChI InChI=1S/C36H43NO7/c1-41-31-24-28(25-32(42-2)34(31)43-3)33(38)35(39)37-23-11-10-22-30(37)36(40)44-29(20-12-18-26-14-6-4-7-15-26)21-13-19-27-16-8-5-9-17-27/h4-9,14-17,24-25,29-30H,10-13,18-23H2,1-3H3
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 1n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of binding to FKBP12 receptor

Bioorg Med Chem Lett 7: 1785-1790 (1997)


Article DOI: 10.1016/S0960-894X(97)00304-1
BindingDB Entry DOI: 10.7270/Q2PZ58TF
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Homo sapiens (Human))		BDBM50474796
PNG
(CHEMBL64941)
Show SMILES Oc1ccc2[nH]c(CN3CCC(Cc4ccc(F)cc4)CC3)nc2c1
Show InChI InChI=1S/C20H22FN3O/c21-16-3-1-14(2-4-16)11-15-7-9-24(10-8-15)13-20-22-18-6-5-17(25)12-19(18)23-20/h1-6,12,15,25H,7-11,13H2,(H,22,23)
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 1.10n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for in vitro inhibition of [3H][(E)-N-(2-methoxybenzyl)cinnamamidine binding to human NR1a/NR2B receptors expressed in LtK-cel...

J Med Chem 47: 2089-96 (2004)


Article DOI: 10.1021/jm030483s
BindingDB Entry DOI: 10.7270/Q2348P41
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50124909
PNG
(CHEMBL159744 | N-(3,5-Dimethyl-benzyl)-4-trifluoro...)
Show SMILES Cc1cc(C)cc(CN=C(N)c2ccc(OC(F)(F)F)cc2)c1 |w:8.7|
Show InChI InChI=1S/C17H17F3N2O/c1-11-7-12(2)9-13(8-11)10-22-16(21)14-3-5-15(6-4-14)23-17(18,19)20/h3-9H,10H2,1-2H3,(H2,21,22)
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 1.20n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cells

Bioorg Med Chem Lett 13: 697-700 (2003)


BindingDB Entry DOI: 10.7270/Q2FX78TP
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Homo sapiens (Human))		BDBM50143890
PNG
(2-(4-Benzyl-piperidin-1-ylmethyl)-3H-benzoimidazol...)
Show SMILES Oc1ccc2nc(CN3CCC(Cc4ccccc4)CC3)[nH]c2c1
Show InChI InChI=1S/C20H23N3O/c24-17-6-7-18-19(13-17)22-20(21-18)14-23-10-8-16(9-11-23)12-15-4-2-1-3-5-15/h1-7,13,16,24H,8-12,14H2,(H,21,22)
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 1.5n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for in vitro inhibition of [3H][(E)-N-(2-methoxybenzyl)cinnamamidine binding to human NR1a/NR2B receptors expressed in LtK-cel...

J Med Chem 47: 2089-96 (2004)


Article DOI: 10.1021/jm030483s
BindingDB Entry DOI: 10.7270/Q2348P41
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50212688
PNG
(2-(3,5-dimethyl-benzyl)-5-trifluoromethoxy-2,3-dih...)
Show SMILES Cc1cc(C)cc(CN2Cc3cc(OC(F)(F)F)ccc3C2=N)c1
Show InChI InChI=1S/C18H17F3N2O/c1-11-5-12(2)7-13(6-11)9-23-10-14-8-15(24-18(19,20)21)3-4-16(14)17(23)22/h3-8,22H,9-10H2,1-2H3
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 2n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to NMDA NR2B receptor

Bioorg Med Chem Lett 17: 3997-4000 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.084
BindingDB Entry DOI: 10.7270/Q21J99GV
More data for this
Ligand-Target Pair
Peptidylprolyl isomerase


(Gallus gallus)		BDBM50068564
PNG
(1-(3,3-Dimethyl-2-oxo-butyryl)-piperidine-2-carbox...)
Show SMILES CC(C)(C)C(=O)C(=O)N1CCCCC1C(=O)OCCCc1ccccc1
Show InChI InChI=1S/C21H29NO4/c1-21(2,3)18(23)19(24)22-14-8-7-13-17(22)20(25)26-15-9-12-16-10-5-4-6-11-16/h4-6,10-11,17H,7-9,12-15H2,1-3H3
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 2n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of binding to FKBP12 receptor

Bioorg Med Chem Lett 7: 1785-1790 (1997)


Article DOI: 10.1016/S0960-894X(97)00304-1
BindingDB Entry DOI: 10.7270/Q2PZ58TF
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50212685
PNG
(2-benzofuran-7-ylmethyl-5-trifluoromethoxy-2,3-dih...)
Show SMILES FC(F)(F)Oc1ccc2C(=N)N(Cc3cccc4ccoc34)Cc2c1
Show InChI InChI=1S/C18H13F3N2O2/c19-18(20,21)25-14-4-5-15-13(8-14)10-23(17(15)22)9-12-3-1-2-11-6-7-24-16(11)12/h1-8,22H,9-10H2
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 2.20n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to NMDA NR2B receptor

Bioorg Med Chem Lett 17: 3997-4000 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.084
BindingDB Entry DOI: 10.7270/Q21J99GV
More data for this
Ligand-Target Pair
Histamine H3 receptor


(GUINEA PIG)		BDBM50071342
PNG
(4-Chloro-N-[4-(1H-imidazol-4-yl)-butyl]-N-(4-imida...)
Show SMILES Clc1ccc(cc1)S(=O)(=O)N(CCCCc1cnc[nH]1)CCCCn1ccnc1
Show InChI InChI=1S/C20H26ClN5O2S/c21-18-6-8-20(9-7-18)29(27,28)26(12-2-1-5-19-15-23-16-24-19)13-4-3-11-25-14-10-22-17-25/h6-10,14-17H,1-5,11-13H2,(H,23,24)
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 2.5n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranes

Bioorg Med Chem Lett 8: 2157-62 (1999)


BindingDB Entry DOI: 10.7270/Q23T9GCZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Homo sapiens (Human))		BDBM50474808
PNG
(CHEMBL65314)
Show SMILES CCS(=O)(=O)Nc1ccc2[nH]c(Cc3ccc(Oc4ccccc4)cc3)nc2c1
Show InChI InChI=1S/C22H21N3O3S/c1-2-29(26,27)25-17-10-13-20-21(15-17)24-22(23-20)14-16-8-11-19(12-9-16)28-18-6-4-3-5-7-18/h3-13,15,25H,2,14H2,1H3,(H,23,24)
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 3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for in vitro inhibition of [3H][(E)-N-(2-methoxybenzyl)cinnamamidine binding to human NR1a/NR2B receptors expressed in LtK-cel...

J Med Chem 47: 2089-96 (2004)


Article DOI: 10.1021/jm030483s
BindingDB Entry DOI: 10.7270/Q2348P41
More data for this
Ligand-Target Pair
Peptidylprolyl isomerase


(Gallus gallus)		BDBM50068573
PNG
(1-(2-Oxo-2-phenyl-acetyl)-piperidine-2-carboxylic ...)
Show SMILES O=C(OC(CCCc1ccccc1)CCCc1ccccc1)C1CCCCN1C(=O)C(=O)c1ccccc1
Show InChI InChI=1S/C33H37NO4/c35-31(28-20-8-3-9-21-28)32(36)34-25-11-10-24-30(34)33(37)38-29(22-12-18-26-14-4-1-5-15-26)23-13-19-27-16-6-2-7-17-27/h1-9,14-17,20-21,29-30H,10-13,18-19,22-25H2
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 3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of binding to FKBP12 receptor

Bioorg Med Chem Lett 7: 1785-1790 (1997)


Article DOI: 10.1016/S0960-894X(97)00304-1
BindingDB Entry DOI: 10.7270/Q2PZ58TF
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Homo sapiens (Human))		BDBM50474792
PNG
(CHEMBL63200)
Show SMILES Oc1ccc2[nH]c(Cc3ccc(Oc4ccccc4)cc3)nc2c1
Show InChI InChI=1S/C20H16N2O2/c23-15-8-11-18-19(13-15)22-20(21-18)12-14-6-9-17(10-7-14)24-16-4-2-1-3-5-16/h1-11,13,23H,12H2,(H,21,22)
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 3.20n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for in vitro inhibition of [3H][(E)-N-(2-methoxybenzyl)cinnamamidine binding to human NR1a/NR2B receptors expressed in LtK-cel...

J Med Chem 47: 2089-96 (2004)


Article DOI: 10.1021/jm030483s
BindingDB Entry DOI: 10.7270/Q2348P41
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50212684
PNG
(2-(2-methoxy-benzyl)-5-trifluoromethoxy-2,3-dihydr...)
Show SMILES COc1ccccc1CN1Cc2cc(OC(F)(F)F)ccc2C1=N
Show InChI InChI=1S/C17H15F3N2O2/c1-23-15-5-3-2-4-11(15)9-22-10-12-8-13(24-17(18,19)20)6-7-14(12)16(22)21/h2-8,21H,9-10H2,1H3
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 3.60n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to NMDA NR2B receptor

Bioorg Med Chem Lett 17: 3997-4000 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.084
BindingDB Entry DOI: 10.7270/Q21J99GV
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50124923
PNG
(CHEMBL162080 | N-(3,5-Dimethyl-benzyl)-4-trifluoro...)
Show SMILES Cc1cc(C)cc(CN=C(N)c2ccc(cc2)C(F)(F)F)c1 |w:8.7|
Show InChI InChI=1S/C17H17F3N2/c1-11-7-12(2)9-13(8-11)10-22-16(21)14-3-5-15(6-4-14)17(18,19)20/h3-9H,10H2,1-2H3,(H2,21,22)
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 3.90n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cells

Bioorg Med Chem Lett 13: 697-700 (2003)


BindingDB Entry DOI: 10.7270/Q2FX78TP
More data for this
Ligand-Target Pair
Histamine H3 receptor


(GUINEA PIG)		BDBM50071343
PNG
(4-Chloro-N-[4-(1H-imidazol-4-yl)-butyl]-N-methyl-b...)
Show SMILES CN(CCCCc1cnc[nH]1)S(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C14H18ClN3O2S/c1-18(9-3-2-4-13-10-16-11-17-13)21(19,20)14-7-5-12(15)6-8-14/h5-8,10-11H,2-4,9H2,1H3,(H,16,17)
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 4n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranes

Bioorg Med Chem Lett 8: 2157-62 (1999)


BindingDB Entry DOI: 10.7270/Q23T9GCZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Homo sapiens (Human))		BDBM50474790
PNG
(CHEMBL303832)
Show SMILES Oc1ccc2[nH]c(CN3CCC(Cc4cccc(F)c4)CC3)nc2c1
Show InChI InChI=1S/C20H22FN3O/c21-16-3-1-2-15(11-16)10-14-6-8-24(9-7-14)13-20-22-18-5-4-17(25)12-19(18)23-20/h1-5,11-12,14,25H,6-10,13H2,(H,22,23)
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 4.20n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for in vitro inhibition of [3H][(E)-N-(2-methoxybenzyl)cinnamamidine binding to human NR1a/NR2B receptors expressed in LtK-cel...

J Med Chem 47: 2089-96 (2004)


Article DOI: 10.1021/jm030483s
BindingDB Entry DOI: 10.7270/Q2348P41
More data for this
Ligand-Target Pair
Peptidylprolyl isomerase


(Gallus gallus)		BDBM50068582
PNG
(1-(3,3-Dimethyl-2-oxo-butyryl)-piperidine-2-carbox...)
Show SMILES CC(C)(C)C(=O)C(=O)N1CCCCC1C(=O)OC(CCCc1ccccc1)CCCc1ccccc1
Show InChI InChI=1S/C31H41NO4/c1-31(2,3)28(33)29(34)32-23-11-10-22-27(32)30(35)36-26(20-12-18-24-14-6-4-7-15-24)21-13-19-25-16-8-5-9-17-25/h4-9,14-17,26-27H,10-13,18-23H2,1-3H3
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 5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of binding to FKBP12 receptor

Bioorg Med Chem Lett 7: 1785-1790 (1997)


Article DOI: 10.1016/S0960-894X(97)00304-1
BindingDB Entry DOI: 10.7270/Q2PZ58TF
More data for this
Ligand-Target Pair
Histamine H3 receptor


(GUINEA PIG)		BDBM50071348
PNG
(4-tert-Butyl-N-[5-(1H-imidazol-4-yl)-pentyl]-benze...)
Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)NCCCCCc1cnc[nH]1
Show InChI InChI=1S/C18H27N3O2S/c1-18(2,3)15-8-10-17(11-9-15)24(22,23)21-12-6-4-5-7-16-13-19-14-20-16/h8-11,13-14,21H,4-7,12H2,1-3H3,(H,19,20)
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 5n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranes

Bioorg Med Chem Lett 8: 2157-62 (1999)


BindingDB Entry DOI: 10.7270/Q23T9GCZ
More data for this
Ligand-Target Pair
Histamine H3 receptor


(GUINEA PIG)		BDBM50071340
PNG
(CHEMBL68336 | N-[5-(1H-Imidazol-4-yl)-pentyl]-4-ni...)
Show SMILES [O-][N+](=O)c1ccc(cc1)S(=O)(=O)NCCCCCc1cnc[nH]1
Show InChI InChI=1S/C14H18N4O4S/c19-18(20)13-5-7-14(8-6-13)23(21,22)17-9-3-1-2-4-12-10-15-11-16-12/h5-8,10-11,17H,1-4,9H2,(H,15,16)
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 5.5n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranes

Bioorg Med Chem Lett 8: 2157-62 (1999)


BindingDB Entry DOI: 10.7270/Q23T9GCZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50124908
PNG
(CHEMBL159560 | N-(2-Methoxy-benzyl)-4-trifluoromet...)
Show SMILES COc1ccccc1CN=C(N)c1ccc(OC(F)(F)F)cc1 |w:9.9|
Show InChI InChI=1S/C16H15F3N2O2/c1-22-14-5-3-2-4-12(14)10-21-15(20)11-6-8-13(9-7-11)23-16(17,18)19/h2-9H,10H2,1H3,(H2,20,21)
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 5.70n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cells

Bioorg Med Chem Lett 13: 697-700 (2003)


BindingDB Entry DOI: 10.7270/Q2FX78TP
More data for this
Ligand-Target Pair
Histamine H3 receptor


(GUINEA PIG)		BDBM50071352
PNG
(CHEMBL69594 | N-[4-(1H-Imidazol-4-yl)-butyl]-C-phe...)
Show SMILES O=S(=O)(Cc1ccccc1)NCCCCc1cnc[nH]1
Show InChI InChI=1S/C14H19N3O2S/c18-20(19,11-13-6-2-1-3-7-13)17-9-5-4-8-14-10-15-12-16-14/h1-3,6-7,10,12,17H,4-5,8-9,11H2,(H,15,16)
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 6n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranes

Bioorg Med Chem Lett 8: 2157-62 (1999)


BindingDB Entry DOI: 10.7270/Q23T9GCZ
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50052511
PNG
(8-Methyl-3-(2-oxo-propyl)-1-p-tolyl-1,3,8-triaza-s...)
Show SMILES CN1CCC2(CC1)N(CN(CC(C)=O)C2=O)c1ccc(C)cc1
Show InChI InChI=1S/C18H25N3O2/c1-14-4-6-16(7-5-14)21-13-20(12-15(2)22)17(23)18(21)8-10-19(3)11-9-18/h4-7H,8-13H2,1-3H3
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 6.30n/an/an/an/an/an/an/an/a



Scios Nova, Inc.

Curated by ChEMBL


Assay Description
Affinity to human Bradykinin receptor B2 in CHO cell membranes determined by displacement of [3H]-NPC 17731

J Med Chem 39: 3169-73 (1996)


Article DOI: 10.1021/jm950676i
BindingDB Entry DOI: 10.7270/Q2C24VH9
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50052509
PNG
(1-Cyclohexylmethyl-8-methyl-3-(2-oxo-propyl)-1,3,8...)
Show SMILES CN1CCC2(CC1)N(CC1CCCCC1)CN(CC(C)=O)C2=O
Show InChI InChI=1S/C18H31N3O2/c1-15(22)12-20-14-21(13-16-6-4-3-5-7-16)18(17(20)23)8-10-19(2)11-9-18/h16H,3-14H2,1-2H3
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 6.80n/an/an/an/an/an/an/an/a



Scios Nova, Inc.

Curated by ChEMBL


Assay Description
Affinity to human Bradykinin receptor B2 in CHO cell membranes determined by displacement of [3H]-NPC 17731

J Med Chem 39: 3169-73 (1996)


Article DOI: 10.1021/jm950676i
BindingDB Entry DOI: 10.7270/Q2C24VH9
More data for this
Ligand-Target Pair
Histamine H3 receptor


(GUINEA PIG)		BDBM50071339
PNG
(CHEMBL68475 | N-[4-(1H-Imidazol-4-yl)-butyl]-4-tri...)
Show SMILES FC(F)(F)Oc1ccc(cc1)S(=O)(=O)NCCCCc1cnc[nH]1
Show InChI InChI=1S/C14H16F3N3O3S/c15-14(16,17)23-12-4-6-13(7-5-12)24(21,22)20-8-2-1-3-11-9-18-10-19-11/h4-7,9-10,20H,1-3,8H2,(H,18,19)
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 7n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranes

Bioorg Med Chem Lett 8: 2157-62 (1999)


BindingDB Entry DOI: 10.7270/Q23T9GCZ
More data for this
Ligand-Target Pair
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50052514
PNG
(8-Methyl-3-(2-oxo-propyl)-1-phenyl-1,3,8-triaza-sp...)
Show SMILES CN1CCC2(CC1)N(CN(CC(C)=O)C2=O)c1ccccc1
Show InChI InChI=1S/C17H23N3O2/c1-14(21)12-19-13-20(15-6-4-3-5-7-15)17(16(19)22)8-10-18(2)11-9-17/h3-7H,8-13H2,1-2H3
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 7.70n/an/an/an/an/an/an/an/a



Scios Nova, Inc.

Curated by ChEMBL


Assay Description
Affinity to human Bradykinin receptor B2 in CHO cell membranes determined by displacement of [3H]-NPC 17731

J Med Chem 39: 3169-73 (1996)


Article DOI: 10.1021/jm950676i
BindingDB Entry DOI: 10.7270/Q2C24VH9
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50212687
PNG
(2-(3-chloro-benzyl)-5-trifluoromethoxy-2,3-dihydro...)
Show SMILES FC(F)(F)Oc1ccc2C(=N)N(Cc3cccc(Cl)c3)Cc2c1
Show InChI InChI=1S/C16H12ClF3N2O/c17-12-3-1-2-10(6-12)8-22-9-11-7-13(23-16(18,19)20)4-5-14(11)15(22)21/h1-7,21H,8-9H2
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 8n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to NMDA NR2B receptor

Bioorg Med Chem Lett 17: 3997-4000 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.084
BindingDB Entry DOI: 10.7270/Q21J99GV
More data for this
Ligand-Target Pair
Peptidylprolyl isomerase


(Gallus gallus)		BDBM50068610
PNG
(1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carb...)
Show SMILES CCC(C)(C)C(=O)C(=O)N1CCCCC1C(=O)OCCC(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H35NO4/c1-4-28(2,3)25(30)26(31)29-19-12-11-17-24(29)27(32)33-20-18-23(21-13-7-5-8-14-21)22-15-9-6-10-16-22/h5-10,13-16,23-24H,4,11-12,17-20H2,1-3H3
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 8.30n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of binding to FKBP12 receptor

Bioorg Med Chem Lett 7: 1785-1790 (1997)


Article DOI: 10.1016/S0960-894X(97)00304-1
BindingDB Entry DOI: 10.7270/Q2PZ58TF
More data for this
Ligand-Target Pair
Histamine H3 receptor


(GUINEA PIG)		BDBM50071358
PNG
(3-Chloro-N-[4-(1H-imidazol-4-yl)-butyl]-benzenesul...)
Show SMILES Clc1cccc(c1)S(=O)(=O)NCCCCc1cnc[nH]1
Show InChI InChI=1S/C13H16ClN3O2S/c14-11-4-3-6-13(8-11)20(18,19)17-7-2-1-5-12-9-15-10-16-12/h3-4,6,8-10,17H,1-2,5,7H2,(H,15,16)
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 8.5n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranes

Bioorg Med Chem Lett 8: 2157-62 (1999)


BindingDB Entry DOI: 10.7270/Q23T9GCZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50124892
PNG
((E)-N-Benzyl-3-phenyl-acrylamidine | CHEMBL158874)
Show SMILES N=C(NCc1ccccc1)C=Cc1ccccc1 |w:11.12|
Show InChI InChI=1S/C16H16N2/c17-16(12-11-14-7-3-1-4-8-14)18-13-15-9-5-2-6-10-15/h1-12H,13H2,(H2,17,18)
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 9n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cells

Bioorg Med Chem Lett 13: 697-700 (2003)


BindingDB Entry DOI: 10.7270/Q2FX78TP
More data for this
Ligand-Target Pair
Histamine H3 receptor


(GUINEA PIG)		BDBM50071346
PNG
(4-Chloro-N-[4-(1H-imidazol-4-yl)-butyl]-benzenesul...)
Show SMILES Clc1ccc(cc1)S(=O)(=O)NCCCCc1cnc[nH]1
Show InChI InChI=1S/C13H16ClN3O2S/c14-11-4-6-13(7-5-11)20(18,19)17-8-2-1-3-12-9-15-10-16-12/h4-7,9-10,17H,1-3,8H2,(H,15,16)
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 9n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranes

Bioorg Med Chem Lett 8: 2157-62 (1999)


BindingDB Entry DOI: 10.7270/Q23T9GCZ
More data for this
Ligand-Target Pair
Histamine H3 receptor


(GUINEA PIG)		BDBM50071344
PNG
(CHEMBL71592 | N-[4-(1H-Imidazol-4-yl)-butyl]-4-tri...)
Show SMILES FC(F)(F)c1ccc(cc1)S(=O)(=O)NCCCCc1cnc[nH]1
Show InChI InChI=1S/C14H16F3N3O2S/c15-14(16,17)11-4-6-13(7-5-11)23(21,22)20-8-2-1-3-12-9-18-10-19-12/h4-7,9-10,20H,1-3,8H2,(H,18,19)
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 10n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranes

Bioorg Med Chem Lett 8: 2157-62 (1999)


BindingDB Entry DOI: 10.7270/Q23T9GCZ
More data for this
Ligand-Target Pair
Histamine H3 receptor


(GUINEA PIG)		BDBM50071354
PNG
(CHEMBL69551 | N-[4-(1H-Imidazol-4-yl)-butyl]-benze...)
Show SMILES O=S(=O)(NCCCCc1cnc[nH]1)c1ccccc1
Show InChI InChI=1S/C13H17N3O2S/c17-19(18,13-7-2-1-3-8-13)16-9-5-4-6-12-10-14-11-15-12/h1-3,7-8,10-11,16H,4-6,9H2,(H,14,15)
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 11n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranes

Bioorg Med Chem Lett 8: 2157-62 (1999)


BindingDB Entry DOI: 10.7270/Q23T9GCZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50124918
PNG
(3,4-Dichloro-N-(2-trifluoromethoxy-benzyl)-benzami...)
Show SMILES NC(=NCc1ccccc1OC(F)(F)F)c1ccc(Cl)c(Cl)c1 |w:2.2|
Show InChI InChI=1S/C15H11Cl2F3N2O/c16-11-6-5-9(7-12(11)17)14(21)22-8-10-3-1-2-4-13(10)23-15(18,19)20/h1-7H,8H2,(H2,21,22)
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 12n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cells

Bioorg Med Chem Lett 13: 697-700 (2003)


BindingDB Entry DOI: 10.7270/Q2FX78TP
More data for this
Ligand-Target Pair
Histamine H3 receptor


(GUINEA PIG)		BDBM50071336
PNG
(4-Chloro-N-[5-(1H-imidazol-4-yl)-pentyl]-benzenesu...)
Show SMILES Clc1ccc(cc1)S(=O)(=O)NCCCCCc1cnc[nH]1
Show InChI InChI=1S/C14H18ClN3O2S/c15-12-5-7-14(8-6-12)21(19,20)18-9-3-1-2-4-13-10-16-11-17-13/h5-8,10-11,18H,1-4,9H2,(H,16,17)
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 12n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranes

Bioorg Med Chem Lett 8: 2157-62 (1999)


BindingDB Entry DOI: 10.7270/Q23T9GCZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Homo sapiens (Human))		BDBM50474807
PNG
(CHEMBL304274)
Show SMILES CC(C)S(=O)(=O)Nc1ccc2[nH]c(Cc3ccc(Oc4ccccc4)cc3)nc2c1
Show InChI InChI=1S/C23H23N3O3S/c1-16(2)30(27,28)26-18-10-13-21-22(15-18)25-23(24-21)14-17-8-11-20(12-9-17)29-19-6-4-3-5-7-19/h3-13,15-16,26H,14H2,1-2H3,(H,24,25)
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 15n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for in vitro inhibition of [3H][(E)-N-(2-methoxybenzyl)cinnamamidine binding to human NR1a/NR2B receptors expressed in LtK-cel...

J Med Chem 47: 2089-96 (2004)


Article DOI: 10.1021/jm030483s
BindingDB Entry DOI: 10.7270/Q2348P41
More data for this
Ligand-Target Pair
Peptidylprolyl isomerase


(Gallus gallus)		BDBM50289698
PNG
(1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carb...)
Show SMILES CCC(C)(C)C(=O)C(=O)N1CCCCC1C(=O)OC(CCCc1ccccc1)CCc1ccc(OC)cc1
Show InChI InChI=1S/C32H43NO5/c1-5-32(2,3)29(34)30(35)33-23-10-9-16-28(33)31(36)38-27(15-11-14-24-12-7-6-8-13-24)22-19-25-17-20-26(37-4)21-18-25/h6-8,12-13,17-18,20-21,27-28H,5,9-11,14-16,19,22-23H2,1-4H3
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 15n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of binding to FKBP12 receptor

Bioorg Med Chem Lett 7: 1785-1790 (1997)


Article DOI: 10.1016/S0960-894X(97)00304-1
BindingDB Entry DOI: 10.7270/Q2PZ58TF
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50124919
PNG
(3,4-Dichloro-N-(3-chloro-benzyl)-benzamidine | CHE...)
Show SMILES NC(=NCc1cccc(Cl)c1)c1ccc(Cl)c(Cl)c1 |w:2.2|
Show InChI InChI=1S/C14H11Cl3N2/c15-11-3-1-2-9(6-11)8-19-14(18)10-4-5-12(16)13(17)7-10/h1-7H,8H2,(H2,18,19)
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 16n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cells

Bioorg Med Chem Lett 13: 697-700 (2003)


BindingDB Entry DOI: 10.7270/Q2FX78TP
More data for this
Ligand-Target Pair
Histamine H3 receptor


(GUINEA PIG)		BDBM50071351
PNG
(CHEMBL69456 | N-[4-(1H-Imidazol-4-yl)-butyl]-4-met...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)NCCCCc1cnc[nH]1
Show InChI InChI=1S/C14H19N3O2S/c1-12-5-7-14(8-6-12)20(18,19)17-9-3-2-4-13-10-15-11-16-13/h5-8,10-11,17H,2-4,9H2,1H3,(H,15,16)
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 17n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranes

Bioorg Med Chem Lett 8: 2157-62 (1999)


BindingDB Entry DOI: 10.7270/Q23T9GCZ
More data for this
Ligand-Target Pair
Histamine H3 receptor


(GUINEA PIG)		BDBM50071337
PNG
(CHEMBL69607 | N-[4-(1H-Imidazol-4-yl)-butyl]-4-nit...)
Show SMILES [O-][N+](=O)c1ccc(cc1)S(=O)(=O)NCCCCc1cnc[nH]1
Show InChI InChI=1S/C13H16N4O4S/c18-17(19)12-4-6-13(7-5-12)22(20,21)16-8-2-1-3-11-9-14-10-15-11/h4-7,9-10,16H,1-3,8H2,(H,14,15)
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 17n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranes

Bioorg Med Chem Lett 8: 2157-62 (1999)


BindingDB Entry DOI: 10.7270/Q23T9GCZ
More data for this
Ligand-Target Pair
Histamine H3 receptor


(GUINEA PIG)		BDBM50071356
PNG
(4-tert-Butyl-N-[4-(1H-imidazol-4-yl)-butyl]-benzen...)
Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)NCCCCc1cnc[nH]1
Show InChI InChI=1S/C17H25N3O2S/c1-17(2,3)14-7-9-16(10-8-14)23(21,22)20-11-5-4-6-15-12-18-13-19-15/h7-10,12-13,20H,4-6,11H2,1-3H3,(H,18,19)
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 17n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranes

Bioorg Med Chem Lett 8: 2157-62 (1999)


BindingDB Entry DOI: 10.7270/Q23T9GCZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Homo sapiens (Human))		BDBM50474794
PNG
(CHEMBL66539)
Show SMILES O=S(=O)(Nc1ccc2[nH]c(Cc3ccc(Oc4ccccc4)cc3)nc2c1)c1ccccc1
Show InChI InChI=1S/C26H21N3O3S/c30-33(31,23-9-5-2-6-10-23)29-20-13-16-24-25(18-20)28-26(27-24)17-19-11-14-22(15-12-19)32-21-7-3-1-4-8-21/h1-16,18,29H,17H2,(H,27,28)
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 17n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Compound was evaluated for in vitro inhibition of [3H][(E)-N-(2-methoxybenzyl)cinnamamidine binding to human NR1a/NR2B receptors expressed in LtK-cel...

J Med Chem 47: 2089-96 (2004)


Article DOI: 10.1021/jm030483s
BindingDB Entry DOI: 10.7270/Q2348P41
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50124921
PNG
(CHEMBL159558 | N-(3-Chloro-benzyl)-4-trifluorometh...)
Show SMILES NC(=NCc1cccc(Cl)c1)c1ccc(cc1)C(F)(F)F |w:2.2|
Show InChI InChI=1S/C15H12ClF3N2/c16-13-3-1-2-10(8-13)9-21-14(20)11-4-6-12(7-5-11)15(17,18)19/h1-8H,9H2,(H2,20,21)
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 20n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cells

Bioorg Med Chem Lett 13: 697-700 (2003)


BindingDB Entry DOI: 10.7270/Q2FX78TP
More data for this
Ligand-Target Pair
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