| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein kinase Lck |
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| Ligand | BDBM50074248 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_221516 (CHEMBL841499) |
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| Kd | 1500±n/a nM |
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| Citation |  Llinas-Brunet, M; Beaulieu, PL; Cameron, DR; Ferland, JM; Gauthier, J; Ghiro, E; Gillard, J; Gorys, V; Poirier, M; Rancourt, J; Wernic, D; Betageri, R; Cardozo, M; Jakes, S; Lukas, S; Patel, U; Proudfoot, J; Moss, N Phosphotyrosine-containing dipeptides as high-affinity ligands for the p56lck SH2 domain. J Med Chem42:722-9 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein kinase Lck |
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| Name: | Tyrosine-protein kinase Lck |
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| Synonyms: | 2.7.10.2 | LCK | LCK_HUMAN | LSK | Leukocyte C-terminal Src kinase | Lymphocyte cell-specific protein-tyrosine kinase | Lymphocyte-specific protein tyrosine kinase | P56-LCK | Protein YT16 | Proto-oncogene Lck | Proto-oncogene tyrosine-protein kinase LCK | Src/Lck kinase | T cell-specific protein-tyrosine kinase |
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| Type: | n/a |
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| Mol. Mass.: | 57987.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P06239 |
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| Residue: | 509 |
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| Sequence: | MGCGCSSHPEDDWMENIDVCENCHYPIVPLDGKGTLLIRNGSEVRDPLVTYEGSNPPASP
LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKAN
SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH
YKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWWEDEWEV
PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL
VRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNY
IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK
SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKER
PEDRPTFDYLRSVLEDFFTATEGQYQPQP
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| BDBM50074248 |
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| n/a |
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| Name | BDBM50074248 |
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| Synonyms: | CHEMBL164198 | Phosphoric acid mono-(4-{(S)-2-acetylamino-2-[(S)-1-(4-methoxy-benzylcarbamoyl)-3-methyl-butylcarbamoyl]-ethyl}-phenyl) ester |
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| Type | Small organic molecule |
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| Emp. Form. | C25H34N3O8P |
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| Mol. Mass. | 535.5265 |
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| SMILES | COc1ccc(CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(C)=O)cc1 |
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| Structure | 
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