| Reaction Details |
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 | Report a problem with these data |
| Target | Capsid scaffolding protein |
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| Ligand | BDBM50075177 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_82452 |
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| IC50 | 2000±n/a nM |
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| Citation |  Pinto, IL; Jarvest, RL; Clarke, B; Dabrowski, CE; Fenwick, A; Gorczyca, MM; Jennings, LJ; Lavery, P; Sternberg, EJ; Tew, DG; West, A Inhibition of human cytomegalovirus protease by enedione derivatives of thieno[2,3-d]oxazinones through a novel dual acylation/alkylation mechanism. Bioorg Med Chem Lett9:449-52 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Capsid scaffolding protein |
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| Name: | Capsid scaffolding protein |
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| Synonyms: | Human herpesvirus 2 protease | SCAF_HHV2H | UL26 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66947.39 |
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| Organism: | Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus2) |
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| Description: | ChEMBL_82452 |
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| Residue: | 637 |
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| Sequence: | MASAEMRERLEAPLPDRAVPIYVAGFLALYDSGDPGELALDPDTVRAALPPENPLPINVD
HRARCEVGRVLAVVNDPRGPFFVGLIACVQLERVLETAASAAIFERRGPALSREERLLYL
ITNYLPSVSLSTKRRGDEVPPDRTLFAHVALCAIGRRLGTIVTYDTSLDAAIAPFRHLDP
ATREGVRREAAEAELALAGRTWAPGVEALTHTLLSTAVNNMMLRDRWSLVAERRRQAGIA
GHTYLQASEKFKIWGAESAPAPERGYKTGAPGAMDTSPAASVPAPQVAVRARQVASSSSS
SSFPAPADMNPVSASGAPAPPPPGDGSYLWIPASHYNQLVTGQSAPRHPPLTACGLPAAG
TVAYGHPGAGPSPHYPPPPAHPYPGMLFAGPSPLEAQIAALVGAIAADRQAGGLPAAAGD
HGIRGSAKRRRHEVEQPEYDCGRDEPDRDFPYYPGEARPEPRPVDSRRAARQASGPHETI
TALVGAVTSLQQELAHMRARTHAPYGPYPPVGPYHHPHADTETPAQPPRYPAKAVYLPPP
HIAPPGPPLSGAVPPPSYPPVAVTPGPAPPLHQPSPAHAHPPPPPPGPTPPPAASLPQPE
APGAEAGALVNASSAAHVNVDTARAADLFVSQMMGSR
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| BDBM50075177 |
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| n/a |
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| Name | BDBM50075177 |
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| Synonyms: | (E)-4-(3-Cyano-phenyl)-4-oxo-but-2-enoic acid [(S)-1-(5-methyl-4-oxo-4H-thieno[2,3-d][1,3]oxazin-2-yl)-ethyl]-amide | CHEMBL141684 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H15N3O4S |
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| Mol. Mass. | 393.416 |
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| SMILES | C[C@H](NC(=O)\C=C\C(=O)c1cccc(c1)C#N)c1nc2scc(C)c2c(=O)o1 |
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| Structure | 
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