| Reaction Details |
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 | Report a problem with these data |
| Target | Acetylcholine receptor subunit epsilon |
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| Ligand | BDBM50524708 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1894505 (CHEMBL4396426) |
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| IC50 | 8800±n/a nM |
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| Citation |  Huang, W; Liang, M; Li, Q; Zheng, X; Zhang, C; Wang, Q; Tang, L; Zhang, Z; Wang, B; Shen, Z Development of the "hidden" multifunctional agents for Alzheimer's disease. Eur J Med Chem177:247-258 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acetylcholine receptor subunit epsilon |
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| Name: | Acetylcholine receptor subunit epsilon |
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| Synonyms: | ACHE_RAT | Acetylcholine receptor protein epsilon chain | Achre | Chrne |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54930.09 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1292388 |
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| Residue: | 494 |
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| Sequence: | MTMALLGTLLLLALFGRSQGKNEELSLYHHLFDNYDPECRPVRRPEDTVTITLKVTLTNL
ISLNEKEETLTTSVWIGIEWQDYRLNFSKDDFAGVEILRVPSEHVWLPEIVLENNIDGQF
GVAYDCNVLVYEGGSVSWLPPAIYRSTCAVEVTYFPFDWQNCSLIFRSQTYNAEEVELIF
AVDDDGNAINKIDIDTAAFTENGEWAIDYCPGMIRHYEGGSTEDPGETDVIYTLIIRRKP
LFYVINIIVPCVLISGLVLLAYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKIPETSLS
VPLLGRYLIFVMVVATLIVMNCVIVLNVSLRTPTTHATSPRLRQILLELLPRLLGLSPPP
EDPGAASPARRASSVGILLRAEELILKKPRSELVFEGQRHRHGTWTAAALCQNLGAAAPE
VRCCVDAVNFVAESTRDQEATGEELSDWVRMGKALDNVCFWAALVLFSVGSTLIFLGGYF
NQVPDLPYPPCIQP
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| BDBM50524708 |
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| n/a |
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| Name | BDBM50524708 |
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| Synonyms: | CHEMBL4459614 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H23N3O3 |
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| Mol. Mass. | 329.3935 |
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| SMILES | CC(N(C)C)c1cc(OC(=O)N2CCOCC2)c2ncccc2c1 |
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| Structure | 
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