| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Integrase |
|---|
| Ligand | BDBM50079914 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_90899 (CHEMBL699512) |
|---|
| IC50 | 155000±n/a nM |
|---|
| Citation |  Neamati, N; Turpin, JA; Winslow, HE; Christensen, JL; Williamson, K; Orr, A; Rice, WG; Pommier, Y; Garofalo, A; Brizzi, A; Campiani, G; Fiorini, I; Nacci, V Thiazolothiazepine inhibitors of HIV-1 integrase. J Med Chem42:3334-41 (1999) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Integrase |
|---|
| Name: | Integrase |
|---|
| Synonyms: | Human immunodeficiency virus type 1 integrase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 32231.48 |
|---|
| Organism: | Human immunodeficiency virus 1 |
|---|
| Description: | ChEMBL_90865 |
|---|
| Residue: | 288 |
|---|
| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
|
|
|
|---|
| BDBM50079914 |
|---|
| n/a |
|---|
| Name | BDBM50079914 |
|---|
| Synonyms: | 6-Methoxy-1,10a-dihydro-2,9-dithia-3a-aza-benzo[f]azulene-4,10-dione | CHEMBL111985 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H11NO3S2 |
|---|
| Mol. Mass. | 281.351 |
|---|
| SMILES | COc1ccc2SC(=O)C3CSCN3C(=O)c2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
