| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Integrase |
|---|
| Ligand | BDBM50079929 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_90899 (CHEMBL699512) |
|---|
| IC50 | >1000000±n/a nM |
|---|
| Citation |  Neamati, N; Turpin, JA; Winslow, HE; Christensen, JL; Williamson, K; Orr, A; Rice, WG; Pommier, Y; Garofalo, A; Brizzi, A; Campiani, G; Fiorini, I; Nacci, V Thiazolothiazepine inhibitors of HIV-1 integrase. J Med Chem42:3334-41 (1999) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Integrase |
|---|
| Name: | Integrase |
|---|
| Synonyms: | Human immunodeficiency virus type 1 integrase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 32231.48 |
|---|
| Organism: | Human immunodeficiency virus 1 |
|---|
| Description: | ChEMBL_90865 |
|---|
| Residue: | 288 |
|---|
| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
|
|
|
|---|
| BDBM50079929 |
|---|
| n/a |
|---|
| Name | BDBM50079929 |
|---|
| Synonyms: | 3-(4-Methyl-piperazin-1-ylmethyl)-10-phenyl-4H,10H-9-thia-3a-aza-benzo[f]azulene | CHEMBL113913 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H27N3S |
|---|
| Mol. Mass. | 389.556 |
|---|
| SMILES | CN1CCN(Cc2ccc3C(Sc4ccccc4Cn23)c2ccccc2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
