| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50079906 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_90899 (CHEMBL699512) |
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| IC50 | >1000000±n/a nM |
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| Citation |  Neamati, N; Turpin, JA; Winslow, HE; Christensen, JL; Williamson, K; Orr, A; Rice, WG; Pommier, Y; Garofalo, A; Brizzi, A; Campiani, G; Fiorini, I; Nacci, V Thiazolothiazepine inhibitors of HIV-1 integrase. J Med Chem42:3334-41 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | Human immunodeficiency virus type 1 integrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32231.48 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_90865 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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| BDBM50079906 |
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| n/a |
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| Name | BDBM50079906 |
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| Synonyms: | 10-Hydroxy-10-phenyl-2,3,10,10a-tetrahydro-1H-9-thia-3a-aza-benzo[f]azulen-4-one | CHEMBL325464 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17NO2S |
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| Mol. Mass. | 311.398 |
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| SMILES | OC1(Sc2ccccc2C(=O)N2CCCC12)c1ccccc1 |
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| Structure | 
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