| Reaction Details |
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 | Report a problem with these data |
| Target | DCN1-like protein 1 |
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| Ligand | BDBM50525313 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1896548 (CHEMBL4398583) |
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| Ki | 14±n/a nM |
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| Citation |  Zhou, W; Ma, L; Ding, L; Guo, Q; He, Z; Yang, J; Qiao, H; Li, L; Yang, J; Yu, S; Zhao, L; Wang, S; Liu, HM; Suo, Z; Zhao, W Potent 5-Cyano-6-phenyl-pyrimidin-Based Derivatives Targeting DCN1-UBE2M Interaction. J Med Chem62:5382-5403 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| DCN1-like protein 1 |
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| Name: | DCN1-like protein 1 |
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| Synonyms: | DCN1 | DCN1-like protein 1 | DCNL1_HUMAN | DCUN1 domain-containing protein 1 | DCUN1D1 | DCUN1L1 | Defective in cullin neddylation protein 1-like protein 1 | RP42 | SCCRO | Squamous cell carcinoma-related oncogene | Synonyms=DCN1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30118.96 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_117443 |
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| Residue: | 259 |
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| Sequence: | MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSL
DRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQ
EFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIA
YWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLI
DDFVEFARPQIAGTKSTTV
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| BDBM50525313 |
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| n/a |
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| Name | BDBM50525313 |
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| Synonyms: | CHEMBL4592844 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H12N4S3 |
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| Mol. Mass. | 380.51 |
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| SMILES | Cc1ccc(cc1)-c1nc(SCC#C)nc(Sc2nccs2)c1C#N |
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| Structure | 
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