| Reaction Details |
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 | Report a problem with these data |
| Target | Growth factor receptor-bound protein 2 |
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| Ligand | BDBM50080833 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_72367 (CHEMBL685573) |
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| IC50 | 497±n/a nM |
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| Citation |  Liu, WQ; Vidal, M; Gresh, N; Roques, BP; Garbay, C Small peptides containing phosphotyrosine and adjacent alphaMe-phosphotyrosine or its mimetics as highly potent inhibitors of Grb2 SH2 domain. J Med Chem42:3737-41 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Growth factor receptor-bound protein 2 |
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| Name: | Growth factor receptor-bound protein 2 |
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| Synonyms: | ASH | GRB2 | GRB2 adapter protein | GRB2_HUMAN | Grb2-SH2 | Growth factor receptor-bound protein 2 |
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| Type: | Protein |
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| Mol. Mass.: | 25205.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P62993 |
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| Residue: | 217 |
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| Sequence: | MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
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| BDBM50080833 |
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| n/a |
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| Name | BDBM50080833 |
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| Synonyms: | CHEMBL264635 | [1-[1-(1,2-Dicarbamoyl-ethylcarbamoyl)-2-(4-hydroxy-phenyl)-ethylcarbamoyl]-2-(4-phosphonooxy-phenyl)-ethyl]-carbamic acid 3-amino-benzyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C30H35N6O11P |
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| Mol. Mass. | 686.6063 |
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| SMILES | NC(=O)CC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(N)=O |
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| Structure | 
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