| Reaction Details |
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 | Report a problem with these data |
| Target | Stromelysin-1 |
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| Ligand | BDBM50081864 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_101945 |
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| IC50 | 200±n/a nM |
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| Citation |  Martin, FM; Beckett, RP; Bellamy, CL; Courtney, PF; Davies, SJ; Drummond, AH; Dodd, R; Pratt, LM; Patel, SR; Ricketts, ML; Todd, RS; Tuffnell, AR; Ward, JW; Whittaker, M The synthesis and biological evaluation of non-peptidic matrix metalloproteinase inhibitors. Bioorg Med Chem Lett9:2887-92 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Stromelysin-1 |
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| Name: | Stromelysin-1 |
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| Synonyms: | MMP-3 | MMP3 | MMP3_HUMAN | Matrix metalloproteinase (2 and 3) | Matrix metalloproteinase 3 | Matrix metalloproteinase-3 | Matrix metalloproteinase-3 (MMP-3) | Matrix metalloproteinase-3 (MMP3) | SL-1 | STMY1 | Stromelysin 1 | Transin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 53973.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08254 |
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| Residue: | 477 |
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| Sequence: | MKSLPILLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPV
VKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVN
YTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNV
LAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLY
HSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGTPANCDPALSFDAVS
TLRGEILIFKDRHFWRKSLRKLEPELHLISSFWPSLPSGVDAAYEVTSKDLVFIFKGNQF
WAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEP
GFPKQIAEDFPGIDSKIDAVFEEFGFFYFFTGSSQLEFDPNAKKVTHTLKSNSWLNC
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| BDBM50081864 |
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| n/a |
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| Name | BDBM50081864 |
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| Synonyms: | (2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-methylmethan-2-ylsulfonamido)methyl)-4-oxo-4-(piperidin-1-yl)butanamide | (2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-methylmethylsulfonamido)methyl)-4-oxo-4-(piperidin-1-yl)butanamide | (2R,3R)-3-Cyclopentylmethyl-N-hydroxy-2-[(methanesulfonyl-methyl-amino)-methyl]-4-oxo-4-piperidin-1-yl-butyramide | CHEMBL98044 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H33N3O5S |
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| Mol. Mass. | 403.537 |
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| SMILES | CN(C[C@@H]([C@@H](CC1CCCC1)C(=O)N1CCCCC1)C(=O)NO)S(C)(=O)=O |r| |
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| Structure | 
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