| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuraminidase |
|---|
| Ligand | BDBM50526899 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1901693 (CHEMBL4403915) |
|---|
| IC50 | 2200±n/a nM |
|---|
| Citation |  Ju, H; Xiu, S; Ding, X; Shang, M; Jia, R; Huang, B; Zhan, P; Liu, X Discovery of novel 1,2,3-triazole oseltamivir derivatives as potent influenza neuraminidase inhibitors targeting the 430-cavity. Eur J Med Chem187:0 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuraminidase |
|---|
| Name: | Neuraminidase |
|---|
| Synonyms: | NA | NRAM_I71A1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 52105.18 |
|---|
| Organism: | Influenza A virus (strain A/Memphis/1/1971 H3N2) |
|---|
| Description: | ChEMBL_578382 |
|---|
| Residue: | 469 |
|---|
| Sequence: | MNPNQKIITIGSVSLTIATVCFLMQIAILVTTVTLHFKQYECDSPANNQVMPCEPIIIER
NITEIVYLTNTTIEKEICPKLVEYRNWSKPQCKITGFAPFSKDNSIRLSAGGDIWVTREP
YVSCDPGKCYQFALGQGTTLDNKHSNDTIHDRIPHRTLLMNELGVPFHLGTRQVCIAWSS
SSCHDGKAWLHVCVTGDDKNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVV
MTDGSASGRADTRILFIEEGKIVHISPLSGSAQHVEECSCYPRYPGVRCICRDNWKGSNR
PVVDINVKDYSIDSRYVCSGLVGDTPRNNDRSSNSNCRNPNNDKGNHGVKGWAFDDGNDV
WMGRTISKDSRSGYETFKVIGGWSTPNSKSQINRQVIVDSDNRSGYSGIFSVEGKSCINR
CFYVELIRGREQETRVWWTSNSIVVFCGTSGTYGTGSWPDGADINLMPI
|
|
|
|---|
| BDBM50526899 |
|---|
| n/a |
|---|
| Name | BDBM50526899 |
|---|
| Synonyms: | CHEMBL4543946 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H33FN6O3 |
|---|
| Mol. Mass. | 472.5556 |
|---|
| SMILES | CCC(CC)O[C@@H]1C=C(C[C@H](N)[C@H]1NC(C)=O)C(=O)NCc1cn(Cc2cccc(F)c2)nn1 |r,c:7| |
|---|
| Structure | 
|
|---|
Search and Browse
