| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase |
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| Ligand | BDBM50526909 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1901692 (CHEMBL4403914) |
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| IC50 | 7150±n/a nM |
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| Citation |  Ju, H; Xiu, S; Ding, X; Shang, M; Jia, R; Huang, B; Zhan, P; Liu, X Discovery of novel 1,2,3-triazole oseltamivir derivatives as potent influenza neuraminidase inhibitors targeting the 430-cavity. Eur J Med Chem187:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuraminidase |
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| Name: | Neuraminidase |
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| Synonyms: | Influenza A Virus Neuraminidase | NA | NRAM_I34A1 | Neuraminidase | Neuraminidase A |
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| Type: | Enzyme |
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| Mol. Mass.: | 50124.14 |
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| Organism: | Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) |
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| Description: | P03468 |
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| Residue: | 454 |
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| Sequence: | MNPNQKIITIGSICLVVGLISLILQIGNIISIWISHSIQTGSQNHTGICNQNIITYKNST
WVKDTTSVILTGNSSLCPIRGWAIYSKDNSIRIGSKGDVFVIREPFISCSHLECRTFFLT
QGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGI
SGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECACVNGSCFTIMTDGPSDGLASYKI
FKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIG
YICSGVFGDNPRPEDGTGSCGPVYVDGANGVKGFSYRYGNGVWIGRTKSHSSRHGFEMIW
DPNGWTETDSKFSVRQDVVAMTDWSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPKEKT
IWTSASSISFCGVNSDTVDWSWPDGAELPFSIDK
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| BDBM50526909 |
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| n/a |
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| Name | BDBM50526909 |
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| Synonyms: | CHEMBL4576390 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H33ClN6O3 |
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| Mol. Mass. | 489.01 |
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| SMILES | CCC(CC)O[C@@H]1C=C(C[C@H](N)[C@H]1NC(C)=O)C(=O)NCc1cn(Cc2cccc(Cl)c2)nn1 |r,c:7| |
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| Structure | 
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