| Reaction Details |
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 | Report a problem with these data |
| Target | Glutathione S-transferase omega-1 |
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| Ligand | BDBM50458516 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1902458 (CHEMBL4404680) |
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| Ki | 440±n/a nM |
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| Citation |  Xie, Y; Tummala, P; Oakley, AJ; Deora, GS; Nakano, Y; Rooke, M; Cuellar, ME; Strasser, JM; Dahlin, JL; Walters, MA; Casarotto, MG; Board, PG; Baell, JB Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors. J Med Chem63:2894-2914 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutathione S-transferase omega-1 |
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| Name: | Glutathione S-transferase omega-1 |
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| Synonyms: | GSTO 1-1 | GSTO1 | GSTO1_HUMAN | GSTTLP28 | Glutathione S-transferase omega-1 | Glutathione transferase omega 1 | glutathione S-transferase omega-1 isoform 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27565.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_11172 |
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| Residue: | 241 |
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| Sequence: | MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP
EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
SKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPW
FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG
L
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| BDBM50458516 |
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| n/a |
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| Name | BDBM50458516 |
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| Synonyms: | CHEMBL4210652 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H12Cl2N2O3S |
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| Mol. Mass. | 311.185 |
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| SMILES | CN(C)S(=O)(=O)c1cc(NC(=O)CCl)ccc1Cl |
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| Structure | 
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