| Reaction Details |
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 | Report a problem with these data |
| Target | Histone acetyltransferase KAT5 |
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| Ligand | BDBM50151660 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1904720 (CHEMBL4407078) |
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| IC50 | 2000±n/a nM |
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| Citation |  Huang, M; Huang, J; Zheng, Y; Sun, Q Histone acetyltransferase inhibitors: An overview in synthesis, structure-activity relationship and molecular mechanism. Eur J Med Chem178:259-286 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone acetyltransferase KAT5 |
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| Name: | Histone acetyltransferase KAT5 |
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| Synonyms: | HTATIP | KAT5 | KAT5_HUMAN | TIP60 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 58595.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_796787 |
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| Residue: | 513 |
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| Sequence: | MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTH
ERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPK
EREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAV
AAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRH
RLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTIS
FFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKE
STEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQ
TILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDI
VDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW
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| BDBM50151660 |
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| n/a |
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| Name | BDBM50151660 |
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| Synonyms: | CHEMBL3774630 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H4N2S4 |
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| Mol. Mass. | 232.369 |
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| SMILES | S(Sc1ccns1)c1ccns1 |
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| Structure | 
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