| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor gamma |
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| Ligand | BDBM50075315 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_139152 (CHEMBL747685) |
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| EC50 | 140±n/a nM |
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| Citation |  Willson, TM; Brown, PJ; Sternbach, DD; Henke, BR The PPARs: from orphan receptors to drug discovery. J Med Chem43:527-50 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor gamma |
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| Name: | Peroxisome proliferator-activated receptor gamma |
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| Synonyms: | Nr1c3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG_MOUSE | Pparg |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57593.55 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1453700 |
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| Residue: | 505 |
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| Sequence: | MGETLGDSPVDPEHGAFADALPMSTSQEITMVDTEMPFWPTNFGISSVDLSVMEDHSHSF
DIKPFTTVDFSSISAPHYEDIPFTRADPMVADYKYDLKLQEYQSAIKVEPASPPYYSEKT
QLYNRPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNC
RIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLR
ALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQE
QSKEVAIRIFQGCQFRSVEAVQEITEYAKNIPGFINLDLNDQVTLLKYGVHEIIYTMLAS
LMNKDGVLISEGQGFMTREFLKNLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVII
LSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKVLQKMTDLRQIVTEHVQL
LHVIKKTETDMSLHPLLQEIYKDLY
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| BDBM50075315 |
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| n/a |
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| Name | BDBM50075315 |
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| Synonyms: | 5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(4-trifluoromethyl-benzyl)-benzamide | 5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(4-trifluoromethyl-benzyl)-benzamide(KRP297) | CHEMBL24458 | KRP-297 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H17F3N2O4S |
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| Mol. Mass. | 438.42 |
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| SMILES | COc1ccc(Cc2sc(=O)[nH]c2O)cc1C(=O)NCc1ccc(cc1)C(F)(F)F |
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| Structure | 
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