Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM50086360 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_145496 |
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Ki | 881±n/a nM |
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Citation | Allen, MP; Blake, JF; Bryce, DK; Haggan, ME; Liras, S; McLean, S; Segelstein, BE Design, synthesis and biological evaluation of 3-amino-3-phenylpropionamide derivatives as novel mu opioid receptor ligands. Bioorg Med Chem Lett10:523-6 (2000) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM50086360 |
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n/a |
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Name | BDBM50086360 |
Synonyms: | CHEMBL347531 | N-Cyclohexylmethyl-3-(3-hydroxy-phenyl)-2,2-dimethyl-3-methylamino-propionamide |
Type | Small organic molecule |
Emp. Form. | C19H30N2O2 |
Mol. Mass. | 318.4537 |
SMILES | CNC(c1cccc(O)c1)C(C)(C)C(=O)NCC1CCCCC1 |
Structure |
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