| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50089465 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_38304 |
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| IC50 | 2500±n/a nM |
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| Citation |  Feng, DD; Biftu, T; Candelore, MR; Cascieri, MA; Colwell, LF; Deng, L; Feeney, WP; Forrest, MJ; Hom, GJ; MacIntyre, DE; Miller, RR; Stearns, RA; Strader, CD; Tota, L; Wyvratt, MJ; Fisher, MH; Weber, AE Discovery of an orally bioavailable alkyl oxadiazole beta3 adrenergic receptor agonist. Bioorg Med Chem Lett10:1427-9 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50089465 |
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| n/a |
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| Name | BDBM50089465 |
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| Synonyms: | CHEMBL285458 | N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-(5-octyl-[1,2,4]oxadiazol-3-yl)-benzenesulfonamide |
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| Type | Small organic molecule |
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| Emp. Form. | C31H39N5O4S |
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| Mol. Mass. | 577.737 |
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| SMILES | CCCCCCCCc1nc(no1)-c1ccc(cc1)S(=O)(=O)Nc1ccc(CCNC[C@H](O)c2cccnc2)cc1 |
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| Structure | 
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