| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 1 |
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| Ligand | BDBM50091655 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_143674 (CHEMBL755163) |
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| IC50 | 2.69±n/a nM |
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| Citation |  Balasubramaniam, A; Tao, Z; Zhai, W; Stein, M; Sheriff, S; Chance, WT; Fischer, JE; Eden, PE; Taylor, JE; Liu, CD; McFadden, DW; Voisin, T; Roze, C; Laburthe, M Structure-activity studies including a Psi(CH(2)-NH) scan of peptide YY (PYY) active site, PYY(22-36), for interaction with rat intestinal PYY receptors: development of analogues with potent in vivo activity in the intestine. J Med Chem43:3420-7 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 1 |
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| Name: | Neuropeptide Y receptor type 1 |
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| Synonyms: | NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44399.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y1 NPY1R HUMAN::P25929 |
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| Residue: | 384 |
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| Sequence: | MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLA
LIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQ
CVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMT
DEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKR
RNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNL
LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVS
KTSLKQASPVAFKKINNNDDNEKI
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| BDBM50091655 |
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| n/a |
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| Name | BDBM50091655 |
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| Synonyms: | CHEMBL438411 | [Leu31, Pro34]PYY(YPAKPEAPGEDASPEELSRYYASLAHYLNLLTRPRY) |
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| Type | Small organic molecule |
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| Emp. Form. | C191H288N52O57 |
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| Mol. Mass. | 4224.6446 |
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| SMILES | n/a |
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| Structure | 
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