| Reaction Details |
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 | Report a problem with these data |
| Target | Dihydroorotase |
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| Ligand | BDBM50536773 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1934349 (CHEMBL4480001) |
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| Kd | 67000±n/a nM |
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| Citation |  Rice, AJ; Lei, H; Santarsiero, BD; Lee, H; Johnson, ME Ca-asp bound X-ray structure and inhibition of Bacillus anthracis dihydroorotase (DHOase). Bioorg Med Chem24:4536-4543 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dihydroorotase |
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| Name: | Dihydroorotase |
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| Synonyms: | Dihydroorotase (PyrC) | PYRC_BACAN | pyrC |
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| Type: | Protein |
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| Mol. Mass.: | 46646.28 |
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| Organism: | Bacillus anthracis (Firmicute) |
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| Description: | n/a |
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| Residue: | 428 |
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| Sequence: | MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHV
HLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVL
PYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCE
ENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRV
IRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHEALIEGLLDGTIDM
IATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADT
FGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIA
WQKESALV
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| BDBM50536773 |
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| n/a |
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| Name | BDBM50536773 |
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| Synonyms: | CHEMBL4532317 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H20N2O3S |
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| Mol. Mass. | 296.385 |
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| SMILES | CCS(=O)(=O)N(C)c1ccc(cc1)C(=O)N1CCCC1 |
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| Structure | 
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