| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50094115 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_212725 (CHEMBL818182) |
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| Ki | 150±n/a nM |
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| Citation |  Han, Q; Dominguez, C; Stouten, PF; Park, JM; Duffy, DE; Galemmo, RA; Rossi, KA; Alexander, RS; Smallwood, AM; Wong, PC; Wright, MM; Luettgen, JM; Knabb, RM; Wexler, RR Design, synthesis, and biological evaluation of potent and selective amidino bicyclic factor Xa inhibitors. J Med Chem43:4398-415 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26557.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07477 |
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| Residue: | 247 |
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| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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| BDBM50094115 |
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| n/a |
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| Name | BDBM50094115 |
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| Synonyms: | 2-(5-Carbamimidoyl-1H-indol-3-yl)-N-[5-(2-sulfamoyl-phenyl)-pyridin-2-yl]-acetamide | CHEMBL138709 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20N6O3S |
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| Mol. Mass. | 448.498 |
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| SMILES | NC(=N)c1ccc2[nH]cc(CC(=O)Nc3ccc(cn3)-c3ccccc3S(N)(=O)=O)c2c1 |
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| Structure | 
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