| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histamine H4 receptor |
|---|
| Ligand | BDBM22914 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1973780 (CHEMBL4606598) |
|---|
| Ki | 66±n/a nM |
|---|
| Citation |  Bartole, E; Grätz, L; Littmann, T; Wifling, D; Seibel, U; Buschauer, A; Bernhardt, G UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H J Med Chem63:5297-5311 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histamine H4 receptor |
|---|
| Name: | Histamine H4 receptor |
|---|
| Synonyms: | HH4R | HRH4_MOUSE | Hrh4 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 44272.75 |
|---|
| Organism: | Mus musculus (mouse) |
|---|
| Description: | Cell pellets from SK-N-MC cells transfected with mouse H4 receptor were used in binding assay. |
|---|
| Residue: | 391 |
|---|
| Sequence: | MSESNSTGILPPAAQVPLAFLMSSFAFAIMVGNAVVILAFVVDRNLRHRSNYFFLNLAIS
DFLVGLISIPLYIPHVLFNWNFGSGICMFWLITDYLLCTASVYNIVLISYDRYQSVSNAV
SYRAQHTGIMKIVAQMVAVWILAFLVNGPMILASDSWKNSTNTKDCEPGFVTEWYILTIT
MLLEFLLPVISVAYFNVQIYWSLWKRRALSRCPSHAGFSTTSSSASGHLHRAGVACRTSN
PGLKESAASRHSESPRRKSSILVSLRTHMNSSITAFKVGSFWRSESAALRQREYAELLRG
RKLARSLAILLSAFAICWAPYCLFTIVLSTYPRTERPKSVWYSIAFWLQWFNSFVNPFLY
PLCHRRFQKAFWKILCVTKQPALSQNQSVSS
|
|
|
|---|
| BDBM22914 |
|---|
| n/a |
|---|
| Name | BDBM22914 |
|---|
| Synonyms: | CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide | Thioperamide | US11622967, Compound Thioperamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H24N4S |
|---|
| Mol. Mass. | 292.443 |
|---|
| SMILES | S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
