| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin K |
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| Ligand | BDBM19804 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_48320 |
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| Ki | 44±n/a nM |
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| Citation |  Fenwick, AE; Garnier, B; Gribble, AD; Ife, RJ; Rawlings, AD; Witherington, J Solid-phase synthesis of cyclic alkoxyketones, inhibitors of the cysteine protease cathepsin K. Bioorg Med Chem Lett11:195-8 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin K |
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| Name: | Cathepsin K |
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| Synonyms: | CATK_HUMAN | CTSK | CTSO | CTSO2 | Cathepsin O | Cathepsin O2 | Cathepsin X |
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| Type: | Enzyme |
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| Mol. Mass.: | 36975.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43235 |
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| Residue: | 329 |
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| Sequence: | MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIH
NLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVD
YRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGG
YMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVA
RVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGE
NWGNKGYILMARNKNNACGIANLASFPKM
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| BDBM19804 |
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| n/a |
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| Name | BDBM19804 |
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| Synonyms: | (2S)-4-methyl-N-(4-oxooxolan-3-yl)-2-(quinolin-2-ylformamido)pentanamide | 3-amidotetrahydrofuran-4-one, 16 | CHEMBL62239 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23N3O4 |
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| Mol. Mass. | 369.4143 |
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| SMILES | CC(C)C[C@H](NC(=O)c1ccc2ccccc2n1)C(=O)NC1COCC1=O |r| |
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| Structure | 
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